Abstract
Introduction: Gallstones are common in Indian population and its treatment has shown a decisive shift from open to minimally invasive route. Undoubtedly, laparoscopy requires longer and steeper learning curve and incurs higher cost. However, preferences of patients are changing rapidly due to better level of awareness and availability of healthcare facility.
Aims: To compare laparoscopic Cholecystectomy vs. open Cholecystectomy in patients of cholelithiasis by measuring parameters such as use of Post-operative analgesia, Operative Time, Post-operative hospital stay, morbidity and mortality.
Material and Method: It is a prospective randomized study of 300 Patients of cholelithiasis aged between 20 years to 70 years operated during 2013-2016 at Government Medical College, Bettiah & associated MJK hospital. They were divided into open and laparoscopic Cholecystectomy groups by drawing a lottery. Patient’s written valid informed consent for the particular procedure was taken and the advantages and disadvantages of both the operative procedure were explained in detail to the patients.
Results: The median (range) operation time for laparoscopic cholecystectomy was 55-170 min (mean=105 min) and 38-92 min (mean=70 min) for open cholecystectomy (p<0.001). The use of parenteral analgesics in case of laparoscopic cholecystectomy (Mean no. of days=1.7) is considerably less than open cholecystectomy (Mean no. of days=3.7). Conversion rate in literature in laparoscopic cholecystectomy ranges from 3% to 15% in well trained hands. In our series it was 8 %.
Conclusion: Laparoscopic cholecystectomy is better than open cholecystectomy in terms of post-operative pain, analgesic requirement and early return to work. However, open cholecystectomy is preferable for Surgeons in training and in cases of complicated cholecystectomy.
Keywords: Cholelithiasis; Cholecystitis; Minimally invasive surgery; Laparoscopic cholecystectomy; Open cholecystectomy; Bile duct injury.
References
1. Khuroo MS, Mahajan R, Zargar SA, Javid G, Sapru S (1989) Prevalence of biliary tract disease in India: a sonographic study in adult population in Kashmir. Gut 30: 201-205.
2. Ellis H (2009) John Stough Bobbs: father of gall bladder surgery. Br J Hosp Med (Lond) 70: 650.
3. Traverso LW (1976) Carl Langenbuch and the first cholecystectomy. [Internet]. American journal of surgery p 81-82.
4. Paulino-Netto A (1993) A review of 391 selected open cholecystectomies for comparison with laparoscopic cholecystectomy. Am J Surg 166: 71-73.
5. Cheslyn-Curtis S, Russell RC (1991) New trends in gallstone management. Br J Surg 78: 143-149.
6. Villanova N, Bazzoli F, Taroni F, Frabboni R, Mazzella G, et al. (1989) Gallstone recurrence after successful oral bile acid treatment. A 12-year follow-up study and evaluation of long-term post dissolution treatment. Gastroenterology 97: 726–731.
7. Della Bianca P, Bonvin B (1990) [Lithotripsy of biliary calculi by shock waves. Current possibilities and perspectives]. Helv Chir Acta 56: 913-916.
8. Fromm H (1989) Gallstone dissolution therapy with ursodiol. Patient selection. Dig Dis Sci 34: 36S-38S.
9. Goco IR, Chambers LG (1988) Dollars and cents: minicholecystectomy and early discharge. South Med J 81: 161-163.
10. O’Dwyer PJ, McGregor JR, McDermott EW, Murphy JJ, O’Higgins NJ (1992) Patient recovery following cholecystectomy through a 6 cm or 15 cm transverse subcostal incision: a prospective randomized clinical trial. Postgraduate Medical Journal. BMJ Group 68: 817-819.
11. Mühe E (1992) Long-term follow-up after laparoscopic cholecystectomy. Endoscopy 24: 754-758.
12. Jani K, Rajan PS, Sendhilkumar K, Palanivelu C (2006) Twenty years after Erich Muhe: Persisting controversies with the gold standard of laparoscopic cholecystectomy. Journal of Minimal Access Surgery 2: 49-58
13. Friedman GD (1993) Natural history of asymptomatic and symptomatic gallstones. Am J Surg 165: 399-404.
14. McSherry CK, Ferstenberg H, Calhoun WF, Lahman E, Virshup M (1985) The natural history of diagnosed gallstone disease in symptomatic and asymptomatic patients. Ann Surg 202: 59-63.
15. Meshikhes AW (2002) Asymptomatic gallstones in the laparoscopic era. Journal Of The Royal College Of Surgeons Of Edinburgh 47: 747-478.
16. Lowenfels AB, Domellöf L, Lindström CG, Bergman F, Monk MA, et al. (1982) Cholelithiasis, cholecystectomy, and cancer: a case-control study in Sweden. Gastroenterology 83: 672-676.
17. Lam CM, Murray FE, Cuschieri A (1996) Increased cholecystectomy rate after the introduction of laparoscopic cholecystectomy in Scotland. Gut 38: 282-284.
18. Escarce JJ, Chen W, Schwartz JS (1996) Falling cholecystectomy thresholds since the introduction of laparoscopic cholecystectomy. Jama The Journal Of The American Medical Association 91: 2653-2654.
19. Mulvihill SJ (2003) Surgical management of gallstone disease and postoperative complications. Semin Gastrointest Dis 14: 237-244.
20. Aucott JN, Cooper GS, Bloom AD, Aron DC (1993) Management of gallstones in diabetic patients. Arch Intern Med 153: 1053-1058.
21. Thompson JS, Philben VJ, Hodgson PE (1984) Operative management of incidental cholelithiasis. Am J Surg 148: 821-824.
22. Goldfarb A, Grisaru D, Gimmon Z, Okon E, Lebensart P, et al. (1990) High incidence of cholelithiasis in older patients with homozygous beta-thalassemia. Acta Haematol 83: 120-122.
23. Ware R, Filston HC, Schultz WH, Kinney TR (1988) Elective cholecystectomy in children with sickle hemoglobinopathies. Successful outcome using a preoperative transfusion regimen. Annals of Surgery 208: 17-22.
24. Alponat A, Kum CK, Koh BC, Rajnakova A, Goh PM (2002) Predictive factors for conversion of laparoscopic cholecyst-ectomy. American journal of surgery 21: 254-258.
25. Domínguez LC, Rivera A, Bermúdez C, Herrera W (2011) [Analysis of factors for conversion of laparoscopic to open cholecystectomy: a prospective study of 703 patients with acute cholecystitis]. Cir Esp 89: 300-306.
26. Vecchio R, MacFadyen BV, Latteri S (1998) Laparoscopic cholecystectomy: an analysis on 114,005 cases of United States series. Int Surg 83: 215-219.
27. Butt A (2006) Conversion of laparoscopic to open cholecystectomy-six years experience at Shalamar Hospital, Lahore. Ann King Edward Medcoll 12: 536-538.
28. Barone JE, Lincer RM (1991) Correction: A prospective analysis of 1518 laparoscopic cholecystectomies. N Engl J Med 325: 1517-1518.
29. Lujan JA, Parrilla P, Robles R, Marin P, Torralba JA, et al. (1998) Laparoscopic cholecystectomy vs open cholecystectomy in the treatment of acute cholecystitis: a prospective study. [Internet]. Archives of surgery 173-175.
30. Kane RL, Lurie N, Borbas C, Morris N, Flood S, et al. (1995) The outcomes of elective laparoscopic and open cholecystectomies. J Am Coll Surg 180: 136-145.