Abstract
Aims And Objectives: Bronchiolitis is the most common lower respiratory tract infection among infants in both developed and developing countries. Study aim is to compare the effects of nebulized 3% hypertonic saline, 0.9% saline and Salbutamol in acute bronchiolitis.
Material and Methods: 60 Children of age 1 month to 24 months with clinical diagnosis of acute bronchiolitis were included in the study. Cases were divided into 3 groups randomly – 3% hypertonic saline (HS) as Group A, 0.9% normal saline as Group B and Salbutamol as Group C. Four doses of nebulization at an interval of six hours were given daily to patient of each group till discharge.
Results: Baseline Clinical Severity (CS) scores in 3%HS, 0.9% Normal Saline and Salbutamol groups were 6 ±1, 5.8±1.5 and 5.5±2.5 respectively (p=0.14), which after treatment dropped to 1.0±0.2, 3.19±0.8 and 1.65±0.7 respectively on the 4th day of treatment (p<0.01). Length of hospital stay in 3% HS, 0.9% Normal Saline and Salbutamol groups was 3.0±1.5, 5.0±1.2 and 3.5±1.7 days respectively, which was found to be statistically significant (p= 0.001).
Conclusion: 3% Hypertonic Saline nebulization (without additional bronchodilator) significantly reduces the CS scores and length of hospital stay as compared to 0.9% Normal Saline and Salbutamol nebulization.
Keywords: Bronchiolitis, management, 3 % hypertonic saline nebulization.
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Corresponding Author
Rakesh Ranjan Kumar
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DOI: https://dx.doi.org/10.18535/jmscr/v5i5.204
