Title: A Study to Determine the Clinico-Epidemiological Profile of CMV Seropositive Infants Admitted in a Tertiary Care Hospital
Authors: Dr Pradeep Singh, Dr R.K. Bishnoi, Dr Pramod Sharma, Dr Kiran Suthar, Dr Sheetal Shaktawat, Dr Vikash Katewa
DOI: https://dx.doi.org/10.18535/jmscr/v5i5.115
Abstract
Background: Cytomegalovirus (CMV) infection is a common viral infection in new born and infants the clinical presentation of which is very variable. The objective was to study the clinical and epidemiological profile of CMV seropositive infants admitted in a teaching hospital of Western Rajasthan.
Methods: A prospective study was done in 30 infants who were diagnosed seropositive out of 85 clinically suspected cases of congenital/ acquired CMV infection. The epidemiological, biochemical and hematological profile of these patients was studied and their clinical presentation and associated morbidity was observed.
Results: Males (80.00%) outnumbered females (20.00%) and 90% of infants were from rural background. (76.92%) of the mothers were educated up to 8th standard or less, which was statistically significant (x2=12.03 p<0.001) 10% infants had a length for age < 2SD which was statistically significant when compared to length appropriate for age (n=21. x2=24.03 p<0.05). Pneumonia was the most common (53.33%) morbidity but accounted only for 3.33% mortality and the case fatality was 6.25% which was less than septicemia (33.33%).
Conclusion: CMV is a virus of paradoxes and can be a potential killer or a silent companion and is more prevalent in rural community. The linear growth is compromised the most and lung involvement in form of pneumonia is most frequent morbidity and though liver involved is with raised liver enzymes the synthetic functions of liver is not affected .
Keywords: cytomegalovirus, pneumonia.
