Title: Renal Cell Carcinoma- A Morphological Profile
Authors: Dr Ashida M Krishnan, Dr Meera Arun, Dr Sauda V M
DOI: https://dx.doi.org/10.18535/jmscr/v5i5.36
Abstract
Introduction: Renal Cell accounts for nearly 3% of all adult malignancies globally and comprises 80-90% of all malignant renal tumors in adult life. The morphological parameters like the histopathologic variant and its nuclear grade determine the aggressiveness of Renal Cell Carcinoma.
Methods: 49 cases who underwent radical/partial nephrectomy specimens in a tertiary health care centre over a span of 2years were selected. Their gross and microscopic features were studied and results were correlated with the clinical features.
Results: Renal cell carcinoma shows varying morphologic features in gross and histologic appearance. The predominant histologic variant is Clear cell variant and predominant nuclear grade of tumours was grade II. There was no correlation between clinical features and grading. Radiological studies have a high sensitivity in detecting Renal cell carcinoma.
Conclusion: Thorough evaluation of morphological parameters in Renal Cell Carcinoma is very essential for planning therapy and predicting the disease outcome.
Keywords: Kidney, Renal cell carcinoma, Clear cell carcinoma.
