Title: Early Brain Metastasis in a Case of Aggressive Renal Cell Carcinoma: A Case Report
Authors: Ramakant Tiwari, Rahat Hadi, Ashish Singhal, Satyajeet Rath
DOI: https://dx.doi.org/10.18535/jmscr/v5i2.123
Abstract
Renal cell carcinoma (RCC) accounts for approximately 2% of malignancies worldwide with about 3,00,000 cases diagnosed per year and 1,00,000 deaths with the highest incidence occurring in Western countries.[1]Brain metastasis from RCC occurs approximately in 8% of patients with metastatic RCC (mRCC). The guidelines from the National comprehensive cancer network (NCCN), European Association of Urology (EAU), and American Urological Association (AUA) recommend cerebral imaging only in patients who have symptomatology. The purpose of our case report was to review the presenting symptomatology and to assess prognostic factors for early brain metastasis followed by their overall treatment and survival. Patients presenting with brain metastases from renal cell carcinoma portend a poor prognosis, with a reported median survival of 4-6 months.Here, we present an interesting case report of 58years old male diagnosed as renal cell carcinoma, underwent Right Radical nephrectomy and developed brain metastases within a month of surgery.
Keywords: Brain metastasis, renal cell carcinoma, metastatic RCC.
