Title: Pattern of Cytology, Chemistry and ADA in Pleuro- peritoneal and Cardiac Tuberculosis in a Tertiary Care Hospital
Authors: Dr Aadil Bashir Rather, Dr Hilal Ahmad Wagay, Dr Gh Nabi Dhobi, Dr Ajaz Nabi Koul, Dr Basharat Kasana
DOI: https://dx.doi.org/10.18535/jmscr/v5i2.43
Abstract
Introduction: Tuberculosis (TB) is a infectious disease caused by Mycobacterium tuberculosis. The disease primarily affects lungs, although involvement of other tissues is common especially pleura and peritoneum. In areas with high prevalence of tuberculosis , body fluid analysis for cells , chemistry and ADA can avoid the use of invasive and expensive investigations.
Aims and Objectives: To study the Fluid analysis of Pleuro-Peritoneal and Cardiac Tuberculosis patients at SKIMS, a tertiary care hospital of Kashmir valley.
Methods and Materials: The fluid analysis was done in tubercular serositis (pleural, ascitic and pericardial fluid) along with detection of Adenosine Deaminase levels.
Results and Observation: A total of 74 patients with 35,33 and 6 patients of pleural, abdominal and pericardial tuberculosis respectively were part of study. The cytology showed a mean lymphocyte count of around 78%,77% and 76% respectively in them .Mean protein of around 4.9g/dl ,5.1g/dl and 4.8g/dl was respectively seen in pleural, ascitic and pericardial fluid. Mean LDH of 464, 383 and 616 IU was respectively found in them. Mean ADA in pleural fluid was 72.8(26-150), in ascitic fluid 71 (16-201) and in Pericardial fluid of 77.8(12-81).
Conclusion: The present study shows that a simple, rapid and inexpensive investigations using fluid cytology and chemistry with added advantage of highly sensitive and specific ADA can reduce the burden of using more expensive, time consuming and invasive investigations for diagnosing tuberculosis, especially in resource limited developing countries.
Keywords: Tuberculosis; Serositis; Diagnosis.
