Abstract

Background: Chikungunya Fever is one of the most important arboviral infection of medical significance. It is characterized  by  an  abrupt onset  of  fever  with  severe  arthralgia followed  by constitutional symptoms and  rash  lasting  for 1-7 days. The disease is almost self-limiting and rarely fatal. Chikungunya virus (CHIKV) is a RNA virus belonging to the family Togaviridae, Genus Alpha virus. Our goal in this study was to find out the prevalence of Chikungunya viral infection in a tertiary care hospital with seasonal variation and clinical findings.

Materials and Methods: Serum samples from patients with febrile illness with clinically suspected signs and symptoms of Chikungunya were included in the study. All samples were screened for Chikungunya IgM antibodies by Standard Diagnostic ELISA method.

Results: In our study, from total 100 serum samples 16 (16%) were positive for Chikungunya virus.

Conclusion: From the present study it can be concluded that the Chikungunya cases are on rise. Hence, Chikungunya has become a major public health problem in India. Favorable mosquitogenic condition during monsoon period is primarily responsible for the rapid spread of Chikungunya. Which requires continuous monitoring of the viral circulationin both endemic and non-endemic areas and rapid implementation of Chikungunya control programme. For these infections earlydetection and access to proper medical care will cause lower fatality rate.

Keywords: Chikungunya virus; Immunoglobulin M; Enzyme Linked Immunosorbent Assay.

Ms. Akanksha Tomar

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