Title: A Case of Churg Strauss Syndrome
Authors: Dr Rajput S G, Dr Saoji N R, Dr Bakre A
DOI: https://dx.doi.org/10.18535/jmscr/v5i1.103
Abstract
Eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome) is characterized by asthma, peripheral and tissue eosinophilia, extravascular granuloma formation, and vasculitis of multiple organ systems. It is an uncommon disease with an estimated annual incidence of 1–3 per million. Autoimmunity is the postulated etiologic mechanism of the disease. The characteristic laboratory finding is a striking eosinophilia, which reaches levels >1000 cells/μL in >80% of patients. Approximately 48% of patients have circulating ANCA that is usually antimyeloperoxidase. Histologic demonstration of eosinophilic granulomas is pathognomonic. We report a case of a 42 years old male who presented with asthma, sensorimotor polyneuropathy besides constitutional features viz. weight loss & anorexia.
Keywords-Eosinophilic granulomatosis with polyangiitis, Churg-Strauss syndrome, eosinophilia, ANCA, asthma.
Dr Rajput S G
Lata Mangeshkar Hospital, Hingna Road, Nagpur PIN- 440019
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