Title: Histomorphological Spectrum of Colorectal Polyps
Authors: Dr Shilpa K, Dr Sharath Kumarh H K, Dr Monica G S, Dr Nimmy Mathew
DOI: https://dx.doi.org/10.18535/jmscr/v5i1.91
Abstract
Introduction: Polyp is defined as any mass protruding into the lumen of hollow viscus. The four major types of polyps are juvenile polyp, Peutz-Jeghers polyps, hyperplastic polyps and adenomatous polyps. A fifth lesion, recently recognized but uncommon, is the mixed hyperplastic-adenomatous polyp. However it is only by microscopic examination it is possible to determine whether these polyps are neoplastic or non neoplastic. The neoplastic polyps are of primary importance because they are precursors of invasive adenocarcinoma. For this reason, it is essential to identify these polyps at a sufficiently early stage, when a simple outpatient procedure to remove them caninterrupt the development of colorectal cancer and prevent disease and death.
Aims and Objectives: We retrospectively conducted the study to histomorphologically evaluate the colorectal polyps in our centre.
Materials and Methods: A retrospective study of colorectal polpoidectomy specimens received in the Department of Pathology, Mysore Medical College and Research Institute over a period of June 2012 – June 2016 was conducted. Histopathological examination was done after routine processing and staining with haematoxylin and eosin.
Results: Out of 30 cases studied adenomatous polyp constituted the most common lesions (60%) followed by hyperplastic polyp (20%). Most of the polyps were situated in the rectum with male preponderance.
Conclusion: An understanding of the pathology of colorectal polyps and cancers is necessary in order to deliver the most appropriate therapy and devise effective screening programmes that reduce morbidity and mortality.
Key Words: Colorectal polyps, Adenomas, Adenocarcinoma.
