Title: Kikuchi’s Disease Presenting as Pyrexia of Unknown Origin: A Case Report & Literature Review
Authors: Dr Priya Sahu, Dr Ashish Nigam
DOI: https://dx.doi.org/10.18535/jmscr/v5i1.84
Abstract
We report this case of a 41 year old Indian male who presented as pyrexia of unknown origin along with weight loss and joint pain. The patient underwent extensive laboratory investigations with clinical suspicion of tubercular or viral etiologies; except for elevated ESR and mildly low leukocyte count all the laboratory investigations were normal. Radiological examinations showed generalized lymphadenopathy and hepatosplenomegaly. The final diagnosis was reached by histopathological examination of cervical lymph node, which showed necrotic foci with karyorrhectic and eosinophilic debris surrounded by lymphohistiocytic and mononuclear plasmacytoid cells which are characteristics of Kikuchi-Fujimoto disease (KFD), so-called histiocytic Necrotizing lymphadenitis.
Keywords: Kikuchi-Fujimoto disease, Histiocytic necrotizing lymphadenitis, Lymphadenopathy, Pyrexia of unknown origin.
