Title: An Unusual Case of Solitary Swelling over Forehead: Think Eosinophilic Granuloma
Authors: Aniruddha Ghosh, Partha Pratim Halder, Arunaloke Bhattacharya, Jaydeep Choudhury, Maya Mukhopadhyay
DOI: https://dx.doi.org/10.18535/jmscr/v5i1.78
Abstract
Langerhans cell histiocytosis is a rare disorder in children. Eosinophilic granuloma is the benign variant of this disease. We report the case of eosinophilic granuloma in a 7 years old male child who presented with right sided solitary swelling over right side of forehead associated with mild dull pain. Plain radiography revealed a solitary gap in frontal bone, computed tomography scan gave a better delineation. Fine needle aspiration cytology was done and histopathology clinched the diagnosis of eosinophilic granuloma. Single boggy swelling over scalp bone of a male child should raise the suspicion of eosinophilic granuloma.
Keywords: Eosinophilic granuloma; Langerhans cell; Aspiration cytology.
1. Lichtenstein L, Jeffe HL. Eosinophilic granuloma of bone: With report of a case. Am J Pathol. 1940;16:595–604.
2. Park SH, Park J, Hwang JH, Hwang SK, Hamm IS, Park YM. Eosinophilic granul-oma of the skull: a retrospective analy-sis. Pediatr Neurosurg. 2007;43:97–101.
3. Ando A, Hatori M, Hosaka M, Hagiwara Y, Kita A, Itoi E: Eosinophilic granuloma arising from the pelvis in children: a report of three cases. Upsala J Med Sci.2008, 113 (1): 209-16.
4. Jain A, Alam K, Maheshwari V, Jain V, Khan R. Solitary eosinophilic granuloma of the ulna: Diagnosis on fine needle aspi-ration cytology. J Cytol. 2008;25:153-6.
5. Howarth DM, Gilchrist GS, Mullan BP, Wiseman GA, Edmonson JH, Schomberg PJ. Langerhans cell histiocytosis: Diagn-osis, management and outcome. Cancer. 1999;85:2278–90.
6. Greis PE, Hankin FM. Eosinophilic granuloma. The management of solitary lesions of bone. Clin Orthop Relat Res. 1990;257:204–11.
7. David R, Oria RA, Kumar R, Singleton EB, Lindell MM, Shirkhoda A, Madewell JE: Radiologic features of eosinophilic granuloma of bone. AJR. 1989, 153:
8. Martinez Lage JF, Bermudez M, Martinez Barba E, Fuster JL, Poza M: Epidural hematoma from a cranial eosinophilic gra-nuloma. Child's Nerv Syst. 2002, 18:74-6.
9. Dundon CC, Williams HA, Laipply TC: Eosinophilic Granuloma of Bone. Radiol. 1946, 47: 433.
10. Puertas EB, Milani C, Chagas JC, de Oliveira VM, dos Santos FP, Wajchenberg M, Rodrigues LM, de Souza PS: Surgical treatment of eosinophilic granuloma in the thoracic spine on patients with neurological lesions. J Pediatr Orthop B. 2003, 12 (5): 303-6.
11. Mukhopadhyay S, Mitra PK, Ghosh S. Touton like giant cell in lymph node in a case of langerhans cell histiocytosis. J Cytol. 2007;24:191–2.
12. Flores LG, Hoshi H, Nagamachi S, Ohnishi T, Watanabe K, Fukiyama , Nao IN, Sawada A: Thalliium201uptake in eosinophilic granuloma of the frontal bone:comparison with Technetium99m MDP imaging. J Nucl Med. 1995, 36 (1): 107-10.