Title: Role of Frozen Section in the Intra operative management of Ovarian Neoplasms and Comparing with Final Histopathological Diagnosis – A Prospective Study
Authors: Dr P Maheshwari, Dr H. Anupama
DOI: https://dx.doi.org/10.18535/jmscr/v5i1.70
Abstract
Objectives: To evaluate performance of frozen section in the intraoperative evaluation of ovarian tumors and deciding the extent of surgery.
Design: Two year prospective study
Materials and Methods: Study of 30 patients diagnosed with ovarian tumors needing surgery admitted to department of Obstetrics and Gynecology, Gandhi Hospital (tertiary referral hospital), Secunderabad from September 2009 to August 2011. Data on frozen section analysis compared with final diagnosis on Paraffin section.
Results: 30 patients meeting the eligibility criteria were included in this study. Among them the frozen section diagnoses were benign in 20 (66.7%), border line in 5 (16.6%) and malignant in 5 (16.6%), where as final Histopathological diagnosis was benign in 19 (63.3%), borderline in 4(13.3%) and malignant in 7 (23.3%). Sensitivity for frozen section was 100% benign, 60% border line and 71.4% malignant. Whereas specificity was 90% benign 96% border line and 100% malignant. There were 4 cases with discordance, all of which were under diagnosed by frozen section. Overall accuracy of frozen section analysis was 90%.
Conclusion: Our data confirm that frozen section diagnosis is a reliable method for surgical management of patients with ovarian mass. The results can be used to avoid over treatment or under treatment of ovarian tumors. Mucinous borderline tumors constitute an important group causing diagnostic discrepancies. Hence a good communication established between clinicians and pathologists is necessary to obtain more accurate results and to minimize number of deferred cases.
