Title: Tubal Ectopic Pregnancy and Variation in Platelet Parameters: A Six Years Study in Rural Population of Central India
Authors: Pravin Sukhdevrao Chavhan, Bharat Umakant Patil, Nitin Mrigrajendra Gangane
DOI: https://dx.doi.org/10.18535/jmscr/v5i1.60
Abstract
OBJECTIVE: The aim of our study was evaluate alteration of various platelet parameters such as platelet count, mean platelet volume (MPV) and platelet distribution width (PDW) in tubal ectopic pregnancy in rural population of central India.
METHOD: This was a retrospective study carried out during period of January 2010 to December 2015. Total 107 cases of tubal ectopic pregnancy evaluated in comparison to same number of patient as a control. During this period hemoglobin level and platelet parameters (platelet count, MPV and PDW) were analyzed.
RESULT: In our study we found significant decrease in mean hemoglobin level. The platelet counts were not that much affected. There was significant decrease in MPV (p < 0.001) and increase in PDW (p = 0.012) as compared to control. We also compare these parameters in ruptured versus non-ruptured ectopic pregnancy in which once again we found statistically significant decrease in MPV(p < 0.001) and increase in PDW (p = 0.009).
CONCLUSION: This study was mostly focused on rural population of central India where the rapid diagnostic tests are sometimes are unavailable. Hence decrease in trend in MPV and increase in PDW can be used as a tool to diagnose ectopic pregnancy.
Keywords: Mean platelet volume, platelet distribution width, platelet parameters, Tubal ectopic pregnancy.