Abstract
Transfusion of blood and blood products has proven to be an important aid in saving patient’s life thus strengthening patient care but at the same time it could transmit infections to the recipients. We conducted a retrospective study to evaluate the prevalence of hepatitis B virus (HBV), hepatitis C virus (HCV), human immunodeficiency virus (HIV) and syphilis among blood donors in a tertiary care hospital of SOUTH- EAST RAJASTHAN, an eleven year experience,2001-2011. Blood donors who were selected for the study were either replacement donors or voluntary donors. Seroprevalence of antibodies against HCV and HIV as well as HBsAg antigen was studied by Enzyme linked immunosorbent assay (ELISA) and Rapid plasma reagin was done for syphilis. Out of total 146885 blood donations 29.33% were voluntary donors and 70.67% were replacement donors. 3810 (2.59%) donors had serological evidence of infection with at least one pathogen, either of HIV, HBV, HCV or Syphilis. These included 490(0.33%) with HIV, 2703 (1.84%) with HBV, 153 (0.1%) with HCV and 464 (0.32%) with Syphilis. Blood transfusion is becoming a leading risk factor for spread of these above mentioned infections thus showing need and importance of screening of these infections in blood donations
Key Words: Blood donors; HIV; HBV; HCV; Syphilis; Transfusion transmissible infections (TTI)
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DOI: http://dx.doi.org/10.18535/jmscr/v3i10.57
