Study of the Effect of Low Level Laser Therapy on Bone Repair in Rats

Title: Study of the Effect of Low Level Laser Therapy on Bone Repair in Rats

Authors: Ahmed El Prince Mohamed, Dr Yousry Mahmoud Mostafa, Dr Nashwa Taher Abdel Aziz, Dr Nehal Ahmed Radwan, Hossam El Din Mostafa Mohamed

DOI: http://dx.doi.org/10.18535/jmscr/v3i11.27

Abstract

References

Corresponding Author

Abstract

This study was conducted to determine the effect of low level laser therapy (LLLT) on bone repair in rats. Seventy two rats were assigned randomly into three groups, group (A) consisted of twenty four rats whose bone fracture didn’t receive laser therapy, group (B) consisted of twenty four rats whose bone fracture received He-Ne laser (632.8 nm) and group (C) consisted of twenty four rats whose bone fracture received Ga-As laser (905 nm). Each group was subdivided into three subgroups according to their sacrificing day on 15^th, 30^th and 45^th post- operative days. Assessment of bone fracture healing was done through radiological analysis and histopathological analysis. The results of this study revealed that group (C) showed more complete bone regeneration on 15^th and 30^th post-operative days when compared with groups (A&B) according to the radiological findings. On 15^th and 30^th postoperative days, there was no statistically significant difference between groups (A&B) (p > 0.05) in newly formed blood vessels, fibroblasts, osteiod and bone formation scores. While, there was a significant difference between groups (A&C) and (B&C) in favor of group (C) (p value < 0.05). So, it could be concluded that infrared laser showed a biostimulating effect on bone repair by stimulating the modulation of the initial inflammatory response and anticipating the resolution to normal condition at the earlier periods. However, there were no differences between groups on 45^th post-operative day.

Key words: low level laser therapy- bone repair.

References

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Call For Paper Volume 12 Issue 10 November 2024

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