Comparison of Sublingual, Vaginal and Oral Misoprostol in Cervical Ripening Prior to 1st Trimester Surgical Abortion a Prospective Study

Title: Comparison of Sublingual, Vaginal and Oral Misoprostol in Cervical Ripening Prior to 1^st Trimester Surgical Abortion a Prospective Study

Authors:Dr Jagadevi S, Dr Anupama Suresh, Dr Priya Ballal

DOI: http://dx.doi.org/10.18535/jmscr/v3i11.19

Abstract

References

Corresponding Author

Abstract

Aim: Comparison of sublingual, vaginal and oral misoprostol as a cervical ripening agent 4 hours prior to surgical abortion

Objective: To compare effectiveness and tolerability of misoprostol as cervical ripening agent in 1^st trimester surgical abortion through different routes.

Materials And Methods: Hospital based prospective randomized study in which 144 women were divided into 3 groups sublingual, vaginal and oral group and single dose 400µg misoprostol was administered 4 hours prior to evacuation. Efficacy was assessed on the basis of dilation achieved and duration of procedure, the tolerability was evaluated based on the side effects.

Results: Cervical dilatation achieved in sublingual group was better than the other routes and had statistical significance. Duration of procedure was also lesser in sublingual group compared to oral and vaginal group. Side effects were seen in all groups, but vomiting being more common in oral group, nausea and uterine cramps more common in vaginal group and loose motion was seen only in sublingual group.

Conclusion; Administration of misoprostol by sublingual route is better than the oral and vaginal routes for cervical ripening.

Key words: cervical ripening, misoprostol, dilation, side effects, first trimester abortion

References

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