Abstract
Introduction: The present study was conducted to evaluate the various high resolution computed tomo graphic patterns of interstitial lung diseases, to assess the reversible (active) verses irreversible (fibrotic) interstitial lung disease with follow up examinations and to limit the differential diagnosis and to make the specific diagnosis.
Materials and Methods:A total number of 50 patients with suspected or known interstitial lung disease were studied by high resolution multidetector computed tomography (HRCT) over a period of 24 months.
Results: Idiopathic pulmonaryfibrosis, lymphangitic carcinomatosis, hypersensitivity pneumonitis, rheumatoid arthritis, miliary tuberculosis,nonspecific interstitial pneumonia, acute interstitial pneumonia,pnemocystis carinii pneumonia, cardiogenic pulmonaryedema, SLE, progressive systemic sclerosis, welder”s pnemoconiosis, sarcoidosis, silicosis. were the interstitial lung diseases.
Conclusion: High Resolution Computed Tomography is a standard investigation to identify and quantify anatomic pattern and distribution of various interstitial lung diseases and also evaluates activeness and progression of disease in relation to prognosis and therapy.
Key Words :interstitial lung diseases ,hrct
References
1. Zerhouni EA, Naidich DP, Stitik FP et al. Computed Tomography of pulmonary parenchyma: part--2: Interstitial disease. J Thorac imag 1985; 1:54-64.
2. Lim MK, Im JG, Ahn JM, Kim JH, Lee SK, Yeon KM. Idiopathic pulmonary fibrosis versus pulmonary involvement of collagen vascular disease: HRCT findings. J Korean Med Sci. 1997; 12(6):492-498.
3. Battista G, Zompatori M et al. Progressive worsening of idiopathic pulmonary fibrosis. High resolution computed tomography (HRCT) study with functional correlation: Radiol Med.03; 105(1-2):2-11.
4. Nishiyama O, Taniguchi H, Kondoh Y, Kimura T, Katoh T, Oishi T, Matsumoto S, Yokoi T, Takagi K et al. Familial idiopathic pulmonary fibrosis: Serial high resolution computed tomographic findings in 9 patients: J Comput Assist Tomogr. 2004; 28(4):443-448.
5. Akira M, Sakatani M et al. Idiopathic pulmonary fibrosis: Progression of honeycombing at thin section CT: Radiology. 1993; 189(3):687-691.
6. Nishiyama O, Kondoh Y et al. Serial high resolution CT findings in nonspecific interstitial pneumonia/fibrosis.J Comput Assist Tomogr 2000; 24:41-46.
7. Johkoh T, Ikezoe J, Tomiyama N et al. CT finding in lymphangitis Carcinomatosis of lung: Correlation with histological findings and pulmonary function tests. AJR J Roentgenol. 1992; 158:1217-1222.
8. DA Lynch, CS Rose, D Way, TE King Jr et al. Hypersensitivity pneumonitis: Sensitivity of high resolution CT in a population based study: American Journal of Roentgenology. 1992; 159:469-472.
9. Biederer J, Schnobel A, Muhle C, Gross WL, Heller M, Reuter M et al. Correlation between HRCT findings, pulmonary function tests and bronchoalveolar lavage cytology in interstitial lung disease associated with rheumatoid arthritis: Eur Radiol. 2004; 14(2):272-280.
10. Hong SH, Im JG, Lee IS et al. High resolution CT findings of miliary tuberculosis. J Comput Assist Tomogr 1998; 22:220-224.
11. Elliot TL, Lynch DA et al. High-resolution computed tomography features of nonspecific interstitial pneumonia and usual interstitial pneumonia. J Comput Assist Tomogr.2005; 29(3):339-345.
12. Primack SL, Hartman TE et al.Acute interstiyial pneumonia: radiographic and CT findings in nine patients.Radiology 1992; 188:817-820.
13. 13. Bonaccorsi A, Cancellieri A et al. Acute interstitial pneumonia: Report of series. Eur Respir J 2003; 21(1):187-191.
14. K Ichikodo, Moritaka Suga et al. Acute interstitial pneumonia: Comparison of high resolution CT findings between Survivors and Nonsurvivors. AJR and Crit Care Med. 2002; 165:1551-1556.
15. Bergin CJ, Wirth RL, Berry GJ et al. Pneumocystis carinii pneumonia: CT and HRCT observations. J Comput Assist Tomogr. 1999; 14(5):756-759.
16. Moskovic E, Miller R, Pearson M et al. High resolution computed tomography of pneumocystis carinii pneumonia in AIDS. Clin Radiol. 1990; 42(4):239-243.
17. Storto ML, Kee ST et al. Hydrostatic pulmonary edema: High resolution CT findings. AJR Am J Roentgenol 1995; 165(4):817-820.
18. Ooi GC, Ngan H, Peh WC, Mok MY, Ipm et al. Systemic lupus erythematosus patients with respiratory symptoms: the value of HRCT. Clin Radiol. 1997; 52(10):775-781.
19. Chan TY, Hansell DM et al. Cryptogenic fibrosing alveolitis and the fibrosing alveolitis of systemic sclerosis: Morphologic differences on computed tomographic scan. Thorax 1997; 52:265-270.
20. Yoshii C, Matsuyama J, TakaZawa A, Itot, Yatera K, Hayashi T, Imanaga T, Kido M. Welder’s pneumoconiosis: diagnostic usefulness of high – resolution computed tomography and ferritin determination in bronchoalveolar lavage fluid. Iutern Med. 2002; 41(12):1111 – 1117.
21. Mimori Y et al. Sarcoidosis correlation of HRCT findings with results of pulmonary function tests and serum angiotensin – converting enzyme assay. Kurume med J. 1998; 45(3):247-256.
22. Ziora D, Grzanka P, Mazur B, Niepsuj G et al. BAL from two different lung segments indicated by high resolution computed tomography (HRCT) in patients with sarcoidosis. Evaluation of alveolitis homogeneity and estimation of HRCT usefulness in selection of lung region for BAL. pneumonol Alergol. Pol. 1999; 67(9-10):422-434.
23. Marchiori E, Ferreira A, Saez F, Gabetto JM, Souza AS Jr, Escuissato DL, Gasparetto EL et al. Conglomerated masses of silicosis in sand blasters: high – resolution CT findings. Eur J Radiol. 206; 59(1):56-59.
24. Ferreira AS, Mareiva VB, Ricardo HM, Coutinho R, Gabetto JM et al. Progressive massive fibrosis in silica exposed workers high resolution computed tomography findings, J Bras Pneumol 2006;32(6):523-528.