Title: Carcinosarcoma of the Oropharynx: A Case Report and Review of Literature

Authors: Dr Shobana Vallabhaneni, Dr Kanika Sharma, Dr Amar Bhatnagar, Dr Hemamalini Aiyer, Dr Garima Rawat

 DOI: https://dx.doi.org/10.18535/jmscr/v9i5.22

Abstract

The co-existence of carcinoma and sarcoma within the same tumor, termed as carcinosarcoma is an exceedingly rare condition which requires skilled oncopathologists to make the accurate diagnosis with the aid of histopathology combined with immunohistochemistry. The literature on the management of this entity is extremely sparse that it requires prospective studies to understand its etiopathogenesis, clinical course and ideal management techniques. The present knowledge inclines towards surgery as a primary treatment option with or without adjuvant radiotherapy depending upon the adverse features. We describe here a case of a 62-year-old gentleman who presented with complaints of dysphagia for a short duration with histopathology revealing carcinosarcoma of the oropharynx and immunohistochemistry depicting spindle cell squamous cell carcinoma with heterologous chondrosarcomatous and osteosarcomatous differentiation.

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Corresponding Author

Dr Shobana Vallabhaneni

DNB Resident, Radiation Oncology, Dharamshila Narayana Superspecialty Hospital, Delhi, India