Title: Study of IgM seropositivity for Rubella virus in clinically suspected cases of Congenital Rubella infection
Authors: Dr Shaik Nazreen, Dr B. Manjula, Dr P. Kamala
DOI: https://dx.doi.org/10.18535/jmscr/v9i1.14
Abstract
Background: Epidemiological data about Rubella syndrome is scarce and Rubella vaccine is included in the National Immunization schedule (NIS) in India. This study aims to identify IgM seropositivity for Rubella virus in clinically suspected cases of Congenital Rubella.
Materials and Methods: Between January 2017 to March 2018, 15 blood samples of neonates with clinically suspected Rubella were collected and tested for IgM antibodies by ELISA.
Results: Out of 15 samples tested, 3 were positive (20%). All 3 serologically positive cases expired. And the mothers of the children are clinically asymptomatic.
Conclusion: This study documented the threat of Congenital Rubella syndrome (CRS) and importance of antenatal screening for Rubella infection for future prevention of CRS cases which is the part of WHO control program.
Keywords: Rubella virus, IgM seropositivity, CRI, CRS, PDA, antenatal screening.
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