Details
Category: Volume 08 Issue 11 November 2020
Hits: 932

Title: Pattern and Impact of anxiety disorders in chronic kidney disease

Authors: Dr Ezeme MS MBBS, FMCP sych; Dr Okafor UH MBBS, FMCP; Dr Anozie T MBBS

 DOI: https://dx.doi.org/10.18535/jmscr/v8i11.87

Abstract

Background: Many studies have reported the occurrence of anxiety disorder in kidney disease, but only very few have tried demonstrating the relevance and the relative rate of different types of anxiety disorders in chronic kidney disease (CKD).

Aim: To find the distribution of different categories of anxiety disorders and the influence in the management of patients with CKD.

Method: This was a cross-sectional study of consecutive attendees of CKD patients at the renal unit of Enugu State University Teaching Hospital, Enugu using MINI International Neuropsychiatric Inventory, clinical and laboratory parameters collected from the patients` folders. Data were analyzed with statistical package of social science version 20. A p-value of ≤ 0.05 was considered statistically significant and confidence interval was at 95%.

Result: Commonest anxiety disorders found among the participants were panic disorder and generalized anxiety disorder, and 20.3% of them had one type of anxiety disorder or the other. Among these anxious participants, 83.9% of them were on haemodialysis, and 64.52% were classified stage 5 kidney disease.

Conclusion: Anxiety disorder is prevalent in kidney disease, and clinicians should have high index of suspicion since its presence may be indicative of severe disease.

Keywords: Pattern; Impact; Anxiety disorder; Kidney disease.  

References

  1. American Psychiatric Association 2013. Diagnostic and statistical manual of mental disorders, 5th Ed., Arlington, VA, American Psychiatric Association.
  2. Assari S 2018. Chronic kidney disease, anxiety and depression among American blacks; does ethnicity matter? https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687323/ Int J Travel Med Glob Health. 2014 2:133–139.
  3. Campbell EA, Olangunji AT, Oyatokun BO, Adeyemi JD 2014. Psychiatric morbidities and associated factors among individuals with end-stage renal disease in Lagos Nigeria. Nigerian Quarterly Journal of Hospital Medicine; vol 24 (3).
  4. Cohen SD, Cukor D, Kimmel PL 2016. Anxiety in patients treated with haemodialysis. Clin J Am Soc Nephrol; 11: 2250–2255. doi: 10.2215/CJN.02590316.
  5. Cukor D, Coplan J, Brown C, Friedman S, Newville H, Safier M, Spielman LA, Peterson RA, Kimmel PL 2008. Anxiety disorders in adults treated by hemodialysis: a single-center study. Am J Kidney Dis; 52: 128–136.
  6. Cukor D, Coplan J, Brown C, Friedman S, Newville H, Safier M, Spielman LA, Peterson RA, Kimmel PL 2008. Anxiety disorders in adults treated by hemodialysis: a single-center study. Am J Kidney Dis; 52: 128–136.
  7. Cukor D, Coplan J, Brown C, Peterson RA, Kimmel PL 2008. Course of depression and anxiety diagnosis in patients treated with hemodialysis: a 16-monthfollow-up.ClinJAm Soc Nephrol; 3: 1752–1758.
  8. Cukor D, Ver Halen N, Fruchter Y 2013. Anxiety and quality of life in ESRD. Semin Dial;26(3):265–268.
  9. Feroze U, Martin D, Kalantar-Zadeh K, Kim JC, Reina-Patton A, Kopple JD 2012. Anxiety and depression in maintenance dialysis patients: preliminary data of a cross-sectional study and brief literature review. J. Ren. Nutr; 22, 207–210. doi: 10.1053/j.jrn.2011.10.009.
  10. Feroze U, Martin D, Kalantar-Zadeh K, Kim JC, Reina-Patton A, Kopple JD 2012. Anxiety and depression in maintenance dialysis patients: preliminary data of a cross-sectional study and brief literature review. J Ren Nutr; 22:207-210.
  11. Gerogianni KG, Babatsikou PF 2013. Identification of stress in chronic haemodialysis. Health Sci J; 7:169-176.
  12. Gerogianni KS, Babatsikou PF 2014. Psychological aspects in chronic renal failure. Health Sci J; 8:205-214.
  13. Goh ZS, Griva K 2018. Anxiety and depression in patients with end-stage renal disease: impact and management challenges - a narrative review. Int J Nephrol Renovasc Dis; 11:93–102.
  14. Hiricare, Tais Pérez-Dominguez, Armando Rodríguez-Pérez, Miguel A. García-Bello et al 2012. Progression of chronic kidney disease. Prevalence of anxiety and depression in autosomal dominant polycystic kidney disease. Nefrologia; 32 (3): 275-418. DOI: 10.3265/Nefrologia.pre2012.Feb.11379.
  15. Hmwe NT, Subramanian P, Tan LP, Chong WK 2015. The effects of acupressure on depression, anxiety and stress in patients with hemodialysis: A randomized controlled trial. Int J Nur Stud; 52:509-518.
  16. Juergensen PH, Juergensen DM, Wuerth DB, et al 1996. Psychosocial factors and incidence of peritonitis. Adv Perit Dial;12:196–198.
  17. Kendler KS, Hettema JM, Butera F, Gardner CO, Prescott CA 2003. Life event dimensions of loss, humiliation, entrapment and danger in the prediction of onsets of major depressive disorder and generalized anxiety. Arch Gen Psychiatry; 60: 789-796.
  18. Kessler R. C., Chiu W. T., Demler O., Merikangas K. R., Walters E. E. 2005. Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication. Arch. Gen. Psychiatry; 62, 617–627. doi: 10.1001/archpsyc.62.6.617.
  19. Kimmel PL, Thamer M, Richard CM, Ray NF 1998. Psychiatric illness in patients with end-stage renal disease. Am. J. Med; 105, 214–221. doi: 10.1016/S0002-9343(98)00245-9.
  20. Kurella M, Chertow GM, Fried LF, Cummings SR, Harris T, Simonsick E, Satterfield S, Ayonayon H, Yaffe K 2005. Chronic kidney disease and cognitive impairment in the elderly: the health, aging, and body composition study. J Am Soc Nephrol; 16: 2127–2133.
  21. Loosman WL, Rottier MA, Honig A, Siegert CE 2015. Association of depressive and anxiety symptoms with adverse events in Dutch chronic kidney disease patients: a prospective cohort study. BMC Nephrol;16(1):155.
  22. Merlino G, Piani A, Dolso P, Adorati M, Cancelli I, Valente M, Gigli GL2006. Sleep disorders in patients with end-stage renal disease undergoing dialysis therapy. Nephrol Dial Transplant; 21: 184–190.
  23. Murtagh FE, Addington-Hall J, Higginson IJ 2007 The prevalence of symptoms in end-stage renal disease: a systematic review. Adv Chronic Kidney Dis; 14: 82–99.
  24. Robinson J, Sareen J, Cox BJ, Bolton JM 2011. Role of self-medication in the development of comorbid anxiety and substance use disorders: a longitudinal investigation. Arch Gen Psychiatry; 68: 800–807.
  25. Sheehan DV, Lecrubier Y, Sheehan KH, Amorim P, Janav SJ, Weiller E et al 1998. The Mini-International Neuropsychiatric Interview (M.I.N.I.): The development and Validation of a Structured Diagnostic Psychiatric Interview for DSM-IV and ICD-10. J Clin Psychiatry; 59(suppl 20): 22-33.
  26. Stein MB, Sareen J 2015. Generalized Anxiety Disorder. N Engl J Med, 373: 2059–2068.
  27. Stein MB, Sareen J 2015. Generalized Anxiety Disorder. N Engl J Med; 373: 2059–2068.
  28. Wruk-Złotowska A 2006. Lęki pacjentów dializowanych. Pielęgniarstwo Polskie; 2:158-166.

Corresponding Author

Dr Ezeme Mark Sunday

Enugu State University of Science and Technology, Enugu Nigeria