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Category: Volume 08 Issue 11 November 2020
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Title:  Comparison of Intrathecal Chloroprocaine 1% Vs Levobupivacaine 0.5% in Patient for Lower Limb Surgery

Authors: Dr Rachit Sinha, Dr Akash Gupta, Dr Neeharika Arora, Dr Malti Agarwal, Dr Rampal Singh, Dr Ishan Verma

 DOI: https://dx.doi.org/10.18535/jmscr/v8i11.50

Abstract

Background and Aims: With the advent of newer drug in spinal Anaesthesia, there is a lacuna in the study of these drugs. Use of longer acting Local Anaesthetics in lower dose has been the practice for shorter Surgery. The study aims to compare Chloroprocaine with the Levobupivacaine in lower limb surgeries of shorter duration.

Methods: A Prospective, Comparative study was conducted after obtaining the permission from Ethical Committee. A total of 70 patients (men & women, 18-60 years, ASA 1-2) posted for elective lower long surgery were included. They were randomly divided into 2 groups. Group A received 1% Chloroprocaine 3ml (30 mg) while Group B received 0.5% Levobupivacaine 3ml (15mg). The Onset of sensory blockade and motor blockade, Peak height for sensory block, two-segment regression time, Duration of sensory block and motor block were studied.

Results: The Onset of sensory blockade & motor blockade was similar in both the groups.  The Peak height for sensory block was higher in Group B (T4 - T6 vs T6 – T8) as compared from Group A, and it also had a longer two-segment regression time (119.31 ± 34.87 mins vs 43.06 ± 8.75 min). The duration of sensory block was shorter in Group A (74.43 ± 10.96 mins vs 312.71 ± 51.94 mins). The duration of motor block was shorter in Group A (61.03 ± 11.48 mins vs 249.57 ± 38.34 mins). All the differences were statistically significant (p<0.05)

Conclusion: We conclude Chloroprocaine is better for shorter lower limb and ambulatory surgery.

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Corresponding Author

Dr Akash Gupta

Assistant Professor, Department of Anaesthesiology, Rohilkhand Medical College, Bareilly