Title: Comparison of Magnesium Sulphate and Dexmeditomidine as an Adjuvant to 0.5% Ropivacaine in Infraclavicular Brachial Plexus Block
Authors: Dr Jipal G. Prajapati, Dr Dipak Raval
DOI: https://dx.doi.org/10.18535/jmscr/v8i11.34
Abstract
Background and Aims: The comparison of dexmeditomidine and magnesium sulphate for sedation and post-operative analgesia as an adjuvant to Ropivacaine 0.5% in Infraclavicular block.
Materials and Methods: Aprospective, randomized, double blind study was conducted on 60 patients of American society of Anaesthesiologists physical status I,II,III aged between 18 to 60 years, weighing between 30 to 90 kg posted for upper limb surgeries under infraclavicular block. The patients were randomly allocated into two groups of 30 each to receive either 35 ml of inj ropivacaine 0.5% with inj Megnesium sulphate (150 mg) 1.5 ml with 2.5 ml 0.9% normal saline (total volume 39 ml) group MS or 35 ml of inj. Ropivacaine 0.5% with inj. Dexmeditomidine (100 µg) 1 ml with 3 ml of 0.9% normal saline (total volume 39 ml) group D. The onset time of sensory block and motor block, duration of surgery, duration of motor blockade and post-operative analgesia, visual analog scale score, compare sedation score, vital parameters, and adverse effects compared between these two groups.
Results: The mean duration of surgery in group MS was longer( 84.33 ± 22.69 min) compared to group D (96 ± 17.73 min),The mean onset time of complete sensory and motor bock in group MS was longer (17.33 ± 1.49 min;21.33 ± 1.75 min) compared to group D (7.6 ± 1.329 min;10.2 ± 1.67 min),total duration of sensory and motor block in group MS was shorter (349 ± 25.91 min;288 ± 26.35 min) as compared to group D (590.33 ± 27.97 min;398.66 ± 26.48 min),The mean duration of analgesia was longer in group D (664.33 ± 30.02 min) as compared to group in MS (386 ± 30.69 min).all results were statistically significant (P < 0.001). No significant side effects were observed in any of the two groups.
Conclusion: Inj. Dexmeditomidine as an adjuvant to Inj. Ropivacaine compared to Magnesium sulphate as an adjuvant to Inj. Ropivacine in Infraclavicular brachial plexus block for upper limb surgery fastens the onset time for sensory and motor block and prolongs the duration of sensory and motor blocks with longer duration of postoperative analgesia.
Keywords: Analgesia, Dexmeditomidine, Magnesium sulphate, Ropivacaine, Infraclavicular brachial plexus.
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