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Category: Volume 08 Issue 07 July 2020
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Title: Histo-pathological study of Medulloblastoma at tertiary care center: A 3 year retro-prospective study

Authors: Dr Arvindra Rahul, Dr Sudha Iyengar, Dr K S Mangal, Dr Ajay Patel

 DOI: https://dx.doi.org/10.18535/jmscr/v8i7.106

Abstract

Aim: Medulloblastoma is one of the most common brain tumors in the pediatric age group. Being of common occurrence, the epidemiology should be well understood to help in the management. The aim of present study is to analyze and correlate the clinicopathological features of medulloblastoma in a tertiary care center.

Method: It is a retro-prospective study from October 2015 to October 2018 (3 years) conducted in Department of Pathology, Gajraraja medical college Gwalior. Demographic data and clinical parameters of 19 cases were recorded and subsequently histopathology was studied. Data was analyzed and variables were correlated.

Results: Majority of patients were males (68.42%) and of less than 12 years of age (78.94%). Most common presenting complaint was headache (89.47 %) and frequent clinical finding was raised intracranial pressure (89.47) and hydrocephalus (84.21%). All of the tumors were located in infratentorial region of brain. Histologically all the tumors were of classical variant except for one case which was diagnosed as desmoplatic variant on histology.

Conclusion: Medulloblastoma is a common malignancy in the pediatric population, accounting for 25% of all childhood brain tumors and relatively uncommon in adults. Surgery is the mainstay of treatment followed by craniospinal irradiation. Histological confirmation of all posterior fossa tumors is essential for the management of this potentially curable tumor.

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Corresponding Author

Dr Sudha Iyengar

Professor, Department of Pathology, G. R. Medical College, Gwalior, MP, India