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Category: Volume 08 Issue 07 July 2020
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Title: To Study Clinicopathological Correlation of Granulomatous Diseases of Skin

Authors: Dr Jasmine Chug, Dr Tavleen Kaur, Dr Navneet Kaur

 DOI: https://dx.doi.org/10.18535/jmscr/v8i7.69

Abstract

Granulomatous lesions in skin can be due to infectious and non infectious causes. Tuberculosis, leprosy, fungus, HIV, granuloma annulare, sarcoidosis, foreign body etc. all can lead to cutaneous granulomas. They present with a variety of overlapping symptoms like papules, nodules or plaques. So detailed clinical history, a good clinical examination and a close histological examination all can lead to conclusive clinicopathological correlation which is essential in making a final diagnosis. In the present study, 50 cases clinically diagnosed as granulomatous lesions of skin were studied, to find the etiology, clinicopathological correlation and relative frequency of all granulomatous lesions on tissue biopsy sent for histopathological examination. The study was done by routine H & E (Haematoxylin and Eosin) staining. Special stains like Ziehl-Neelsen stain, Gomori's Methenamine silver, PAS, Fite Faraco were also done wherever required. The overall level of concordance between clinical and histopathological diagnosis was noted in 78% cases. Parity for individual type of leprosy was TT (50%), BT (92.3%), BB (0%). Parity for other cases, LV (57.14%), S (66.6%), F (0%) and for GA, TVC, LS, SC 100% each.

Keywords: Granuloma, Leprosy, Granulomatous Dermatitis

Keynote: To find the etiology, clinicopathological correlation and relative frequency of all granulomatous lesions of skin on tissue biopsy sent for histopathogical examination.

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Corresponding Author

Dr Jasmine Chug

Senior Resident, Department of Pathology, Govt Medical College Amritsar, India