Title: Chronic Fungal Rhinosinusitis due to Aspergillosis: A Case Report

Authors: Lekshmi Vijayamohanan, Sarita Asotra, Madhuri Dhadwal, Ankita Dheer

 DOI: https://dx.doi.org/10.18535/jmscr/v8i7.31

Abstract

Aspergillosis is a ubiquitous mold causing allergic bronchopulmonary aspergillosis in healthy people and invasive disease, pneumonia and serious sinusitis in immunocompromised patients. It’s characteristic morphologic features distinguish it from other fungi and aid diagnosis in an otherwise unremarkable case of nasal polyposis. We report a case of a 59 year old lady with chronic rhino sinusitis caused by Aspergillosis, where histopathology played a key role in diagnosis.

Keywords: Aspergillus, rhinosinusitis, histopathology, Humans, Female, Middle Aged, Young Adult, Adult, Aspergillosis, Allergic Bronchopulmonary.

References

  1. Plaignaud X. Observation sur un fongus du sinus maxillarie. J Clin 1791;1:111.
  2. Alam, B. N. Chander, G. S. Sabhikhi, and M. Bhatia, “Sinonasal mucormycosis: diagnosis using computed tomog- raphy,” Medical Journal Armed Forces India, vol. 59, no. 3, pp. 243–245, 2003.
  3. Chakrabarti, A. Das, J. Mandal et al., “The rising trend of invasive zygomycosis in patients with uncontrolled diabetes mellitus,” Medical Mycology, vol. 44, no. 4, pp. 335–342, 2006.
  4. Malhotra, S. Duggal, N. K. Bhatia, N. Sharma, and C. Hans, “Rhinocerebral zygomycosis with pulmonary aspergillosis in a non-HIV-infected patient: an unusual case report from India,” Journal of Medical Microbiology, vol. 58, no. 1, pp. 146–150, 2009.
  5. Abedi, A. Sismanis, K. Choi, and P. Pastore, “25 years’ expe- rience treating cerebro-rhino-orbital mucormycosis,” Laryn- goscope, vol. 94, no. 8, pp. 1060–1062, 1984.
  6. E. Bennett, “Aspergillosis,” inHarrison’s Principles of Internal Medicine, K. J. Isselbacher, J. Wilson, A. Fauci, E. Braunwald, J. Martin, and D. Kasper, Eds., pp. 855–862, McGraw Hill, New York, NY, USA, 2005.
  7. Allphin AL, Strauss M, Abdul-Karim FW. Allergic fungal sinusitis: problems in diagnosis and treatment. Laryngoscope. 1991;101:815-820.
  8. Collins MM, Nair SB, Wormald PJ. Prevalence of noninvasive fungal sinusitis in South Australia. Am J Rhinol. 2003;17:127-132.
  9. Bent JP, Kuhn FA. Diagnosis of allergic fungal sinusitis. Otolaryngol Head Neck Surg. 1994;580-588.
  10. Sharma OP, Chwogule R. Many faces of pulmonary aspergillosis. Eur Respir J. 1998;12:705–15.
  11. Kumar, V., Abbas, A. and Aster, J., 2013. Robbins Basic Pathology. 9th ed. Elsevier Saunders, pp.388,389.
  12. deShazo RD, Chapin K, Swain R. Fungal sinusitis. N Eng J Med 1997;337:254-59.

Corresponding Author

Sarita Asotra

IGMC Shimla