Title: Study of Metabolic Syndrome with Special Reference to Thyroid Profile Abnormality from Central India
Authors: Dr Dharmendra Jhavar, Dr Pooja Sounr, Dr Pinki Sharma, Dr Ambar Khalwadekar
DOI: https://dx.doi.org/10.18535/jmscr/v8i7.25
Abstract
Introduction: Metabolic syndrome (MS) is a cluster of various clinical and biochemical abnormalities which include obesity, systemic hypertension, hypertriglyceridemia, low HDL and raised fasting blood sugar levels. The thyroid hormone has influence on almost each and every cell of various organs in the body. Its deficiency or excess is likely to have various metabolic abnormalities.
Methods: This cross sectional observational study was conducted in 100 consecutive patients of metabolic syndrome at MGM Medical College and MY Hospital Indore, MP, India from one year of study duration and both outdoor and in patients were included in this study.
Results: In this study, out of total 100 patients, 60 were females and 40 were males. Most patients (40%) were in age group of 41-50 years. Euthyroid, hypothyroid, subclinical hypothyroid, hyperthyroid, and subclinical hyperthyroid were found in 76%, 4%, 19%, 0% and 1% respectively. Out of 100 MS patients, 39% fulfilled 3 out of 5 criteria, 38% patients fulfilled 4 out of 5 criteria, and 23% patients fulfilled all 5 criteria of MS. A ‘p-value’ was found to be 0.342, which was statistically not significant. Mean (SD) Waist circumference in euthyroid and subclinical hypothyroid patients were 92.78(10.04) cm and 98.68(10.83) cm respectively and it was statistically significantly high (p value = 0.026). Mean (SD) BMI in euthyroid and subclinical patients were 27.31(4.37) and 29.87(5.47) respectively and it was statistically significant (p value= 0.033).
Conclusions: Prevalence of hypothyroidism and subclinical hypothyroidism is more common in metabolic syndrome patients. Waist circumference and BMI were significantly high in subclinical hypothyroid patients as compared to euthyroid patients.
Keywords: Euthyroid, hypothyroid, subclinical hypothyroid, metabolic syndrome.
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