Title: A Cross Sectional Study to Assess Adherence in Type 2 Diabetes Mellitus Outpatients Using Moriskys Medication Adherence Scale-4

Authors: Dadhich J, Bhargava J, Jain M, Sharma K, Singh A, Kakkar S, Chandel R

 DOI: https://dx.doi.org/10.18535/jmscr/v8i7.11

Abstract

Introduction: Adherence to prescribed medication is a crucial part of patient care and indispensable for reaching clinical goals. In view of long duration of diabetes, there is a requirement to observe adherence to anti diabetic drugs by patients. In this study 4-item Morisky Medication Adherence Scale (MMAS-4) has been used which is validated in the broadest range of diseases and also in patients with low literacy hence is the most widely used scale for research purposes.

Methodology: It was a cross-sectional descriptive observational study for duration of 12 months. A total 400 known patients of type 2 diabetes mellitus from endocrinology outdoor of tertiary care hospital, were recruited and data collected. Adherence to antidiabetics was assessed using Morisky’s medication adherence score (four point).

Results: Most commonly observed age group was of 40-50 years (mean age 53.76 + 8.84), with male preponderance (57.5%). 67.5% of total were obese (mean BMI 29.79 + 3.26). Adherence to treatment was medium in 66% of the patients.

Conclusion: The adherence observed to treatment in the study was not satisfactory and a multi – faceted approach is needed to improve adherence.

References

  1. Dobbels F, Van Damme-Lombaert R, Vanhaecke J, De Geest S. Growing pains: non-adherence with the immunosuppressive regimen in adolescent transplant recipients. Pediatr Transplant Jun;9(3):381-390 .
  2. Brown MT, Bussell JK. Medication adherence: WHO cares?. Mayo Clin Proc. 2011;86(4):304‐314. doi:10.4065/mcp.2010.0575.
  3. Lam WY and Fresco P. Medication Adherence Measures: An Overview. BioMed Research International 2015; Article ID 217047, 12 pages. https://doi.org/10.1155/2015/217047
  4. Brahmbhatt SV, Sattigeri BM, Nil AK, Parikh DP, Shah HS. A prospective study on drug utilization pattern & rationality in treatment of type II diabetes mellitus: a population based analysis. Int J Res Med Sci 2014; 2: 983-987.
  5. Mandal S, Maiti T, Das AK, Das A, Mandal A, Sarkar BS et al. Drug utilization study in patients with type 2 diabetes mellitus diabetes clinic of a tertiary care hospital in rural Bengal. Int J Basic Clin Pharmacol 2016; 5:1647-54.
  6. Ahmed Z, Hafez MA, Bari MA, Akhter J. Pattern of anti-diabetic drugs prescribed in a tertiary care hospital of Bangladesh. Int J Basic Clin Pharmacol 2016; 5(1): 6-12
  7. Nguyen KT, Diep BTT, Nguyen VDK, Lam HV, Tran KQ & Tran NQ. A cross-sectional study to evaluate diabetes management, control and complications in 1631 patients with type 2 diabetes mellitus in Vietnam (DiabCare Asia). International Journal of Diabetes in Developing Countries: https://doi.org/10.1007/s13410-019-00755-w
  8. IDF Diabetes Atlas 9th edition 2019 [Internet]. IDF Diabetes Atlas 9th edition 2019. [cited 2019Dec17]. Available from: https://www.diabetesatlas.org/
  9. Dutta S, Beg MA, Anjoom M, Varma A, Bawa S. Study of prescribing pattern in diabetes mellitus patients in a tertiary care teaching hospital at Dehradun, Uttarakhand. Int J Med Sci Public Health 2014; 3: 1351-1354.
  10. Sachdev B. Community Based Study On Incidence Of Type 2 Diabetes And Hypertension Among Nomad Tribal Population Of Rajasthan, India. Inter. Jour. of Scie. and Nat., 2011; 2(2): 296 – 301
  11. Iglay K, Hannachi H, Joseph Howie P, Xu J, Li X, Engel SS. Prevalence and co-prevalence of comorbidities among patients with type 2 diabetes mellitus. Curr Med Res Opin  2016; 32(7):1243-1252
  12. Varkey A, Karthikeyan V, Raj A, Joy M, Kiran DR. Studies on drug use pattern in the management of diabetes mellitus in rural teaching hospital Chittur, Kerala. International Journal of Novel Trends in Pharmaceutical Sciences. 2018; 8(1): 15-20.
  13. Desai P, Desai C, Panchal A, Desai S. A Drug Prescribing Pattern Study in Diabetes Mellitus: An Outpatient Study. J Pharm Sci Bio Scientific Res. 2014; 5(1):115-118.
  14. Alqarni AM, Alrahbeni T, Qarni AA, Qarni HMA. Adherence to diabetes medication among diabetic patients in the Bisha governorate of Saudi Arabia - a cross-sectional survey. Patient Prefer Adherence 2019;13: 63–71.
  15. Aloudah NM, Scott NW, Aljadhey HS, Araujo-Soares V, Alrubeaan KA, Watson MC. Medication adherence among patients with type 2 diabetes: A mixed methods study.2018. PLoS ONE. 2018;13:e0207583.
  16. Arulmozhi S.1, Mahalakshmy T. Self Care and Medication Adherence among Type 2 Diabetics in Puducherry, Southern India: A Hospital Based Study. J Clin Diagn Res April;8(4):UC01–3. 10.7860/JCDR/2014/7732.4256.

Corresponding Author

Bhargava J