Title: To Assess the Effectiveness of Low-dose Granisetron on Shivering in epidural block: A prospective randomized controlled study
Authors: Dr Praveen Kumar Tiwari, Dr Shakti Kumar, Dr (Prof) Usha Suwalka
DOI: https://dx.doi.org/10.18535/jmscr/v8i5.82
Abstract
Shivering after central neuraxial blockade is unpleasant not only for patients but for anaesthesiologists as well as it induces hypoxemia, lactic acidosis, increased intraocular pressure and intracranial pressure, increased chances of myocardial ischemia and interference with patient’s monitoring. Serotonin antagonists reduces the incidence of shivering in patients with spinal anesthesia. Granisetron is better than ondansetron with longer half life and fewer side effects. After getting approval from the ethical committee 32 patients aged between 20-50 years of ASA group I &II were studied over a period of 2 months. Patients of test group G were given granisetron 10μg/kg body weight intravenously before anaesthesia whereas group C was control group. The administration of low dose granisetron reduced the incidence of shivering as well as the degree of intensity of shivering post epidural anaesthesia.
Keywords: Shivering, Granisetron, Epidural block.
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