Title: Etioclinical Profile of Urinary Tract Infection in Children

Authors: Dr Susanta Kumar Ghosh, Dr Santosh Kumar Saha, Dr Milia Islam

 DOI: https://dx.doi.org/10.18535/jmscr/v8i4.35

Abstract

   

Objective: In this study our main objective is to assess etioclinical profile of urinary tract infection in children.

Method: This observational study was carried out Tertiary medical college, Dhaka from January 2017 to December 2019 among 100pediatric patients with UTI who attending outpatient and inpatient departments of in department of pediatric. Data were compiled and appropriate statistical package for social science (SPSS). P value <0.05 was taken as minimum level of significance.

Results: In this study, most of the patients belong to 1-5 years age group and 69%and female were 38% higher than male. Also, 75% positive culture of bacteriuria was found in female and most of the patients from rural and only 41% patients treated with antibiotic.

Conclusion: From our study, we can say that E. coli is the most common uropathogen. Antibiotics such as amoxycillin, amoxiclav, cephradine and cefixime. have limited value for the treatment of UTI. Routine observing of susceptibility patterns is necessary, which will help in the empirical treatment of UTI to the clinicians and also for the planning of antibiotic policy of the individual foundation.

Keywords: Urinary tract infections (UTI), antibiotic resistance, amoxicillin.

References

  1. Sobel JD, Kaye D. Urinary tract infections. In: Mandell GL, Bennett JE, Dolin R, editors. Principles and Practice of Infectious Diseases. 5th ed. Philadelphia: Churchill Livingstone; 2000. pp. 773–805. [Google Scholar]
  2. Naveen R, Mathai E. Some virulence characteristics of uropathogenic Escherichia coli in different patient groups. Indian J Med Res. 2005;122:143–7. [PubMed] [Google Scholar]
  3. Wilkie ME, Almond MK, Marsh FP. Diagnosis and management of urinary tract infection in adults. BMJ. 1992;305:1137–41. [PMC free article] [PubMed] [Google Scholar]
  4. Bajaj JK, Karyakarte RP, Kulkarni JD, Deshmukh AB. Changing aetiology of urinary tract infections and emergence of drug resistance as a major problem. J Commun Dis. 1999;31:181–4. [PubMed] [Google Scholar]
  5. Magalit SL, Gler MT, Tupasi TE. Increasing antimicrobial resistance patterns of community and nosocomial uropathogens in Makati Medical Center. Philipp J Microbiol Assoc. 2001;51:94–100. [Google Scholar]
  6. M I Majumder, T Ahmed, D Hossain, S Begum. Bacteriology and antibiotic sensitivity patterns of urinary
  7. tract infections in a tertiary hospital in Bangladesh. Mymensingh Med J. 2014; 23 (1): 99-104. PMid:24584381
  8. García-Morúa A, Hernández-Torres A, Salazar-de-Hoyos JL, Jaime-Dávila R, Gómez- Guerra LS.
  9. Community acquired urinary tract infection etiology and antibiotic resistance in a Mexican population group. Revista Mexicana de Urología. 2009; 69: 45–48.
  10. Boucher HW, Talbot GH, Bradley JS. Bad bugs, no drugs: no ESKAPE! An update from the Infectious Diseases
  11. Society of America. Clinical Infectious Diseases. 2009; 48(1): 1–12.
  12. Khan AU, Musharraf A. Plasmid mediated multiple antibiotic resistance in P. mirabilis isolated from the UTI patients. Medical Sci Mon. 2004; 10: 598-602.
  13. Chin TL, Mac Gowan AP, Bowker KE. Prevalence of antibiotic resistance in Escherichia coli isolated from urine samples routinely referred by general practitioners in a large urban centre in South-west England. J Anti microb Chemother. 2015; 70: 2167-9.
  14. Udur G. Drug resistant cholera in India attributed to antibiotic misuse. BMJ. 2000; 321: 1368-1369.

Corresponding Author

Dr Susanta Kumar Ghosh

Assistant Professor (Pediatric Cardiology), National Institute of Cardiovascular Diseases, Dhaka, Bangladesh