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Category: Volume 08 Issue 04 April 2020
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Title: Relevance and Role of Hydroxychloroquine in Prophylaxis and Therapy of COVID-19

Authors: Dr Arjun Baidya, Dr Anand Shankar, Dr Rishad Ahmed, Dr Amit Kumar Das

 DOI: https://dx.doi.org/10.18535/jmscr/v8i4.18

Abstract

   

A rapidly spreading novel corona virus infection, COVID-19 (Corona virus disease, 2019), a global pandemic has already reported to cause death of approximately 2.5% of total infected individuals. Being more immunodeficient uncontrolled diabetic individuals have more chance to be symptomatic with COVID-19 than the nondiabetic individuals. There are some recent updates regarding the efficacy of hydroxychloroquine as a monotherapy or with adjunct therapy to improves the condition of COVID-19 infected patients and even the molecule hasthe property to regulate blood glucose level without much hypoglycemia. This review article highlighted the proposed mechanisms of hydroxychloroquine by which it provides beneficial effect in nondiabetic individuals who became symptomatic with COVID-19 as well as being an approved anti diabetic agent how it reduces the chance of infection with COVID-19 in patients with diabetes.

Keyword: Hydroxychloroquine, Coronavirus, COVID-19, Diabetes.

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Corresponding Author

Dr Arjun Baidya

Associate Professor, Department of Endocrinology, NRS Medical College & Hospital, Kolkata, West Bengal, India