Title: Podocytopathy with SLE: A Report of Two Cases

Authors: Hana S. Alahmari, Mansour Y. Somaily, Mohammed M. Alomair, Tariq E. Aljohani, Abdulrahman K. Alabdulsalam, Mohammed A. Omair

 DOI: https://dx.doi.org/10.18535/jmscr/v7i9.41

Abstract

    

Background

Lupus podocytopathy is a recently recognised new entity of lupus nephritis characterised by diffuse foot process effacement with or without mesangial expansion. Glomerular proliferation and capillary wall immune deposits were inadequate in the histopathological analysis. Clinically, it is manifesting as nephrotic proteinuria in the majority of reported cases. The knowledge about the epidemiology, precipitant aetiology and choices of management are lacking. Here, we describe 2 cases presented with significant proteinuria secondary to foot process effacement with the absence of immunocomplement deposition or glomerular inflammation.

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Corresponding Author

Hana S. Alahmari

Rheumatology Unit, Department of Medicine, College of Medicine, King Khalid University, Abha, Saudi Arabia