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Category: Volume 07 Issue 09 September 2019
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Title: Analgesic efficacy of single low dose intrathecal labour analgesia using fentanyl (25µg), bupivacaine (2.5mg) and morphine (250µg)

Authors: Dr Rama Thakur, Dr Poonam, Dr Rohini Rao, Dr Sapna Berry, Dr Mayuri Shrivastava, Dr Anshul Rana, Dr Sanjay Rathore

 DOI: https://dx.doi.org/10.18535/jmscr/v7i9.23

Abstract

     

Aim of the study: To evaluate the analgesic efficacy of low dose Intrathecal labour analgesia using fentanyl, bupivacaine and morphine.

Methodology: 100 parturients with uncomplicated pregnancy in spontaneous or induced labor at cervical dilatation 4-6cm were enrolled for the study. They were randomized into two groups of 50 each, using computer based block randomization. Group 1(N=50) received intrathecal labor analgesia using. fentanyl (25µg), bupivacaine (2.5mg) and morphine (250µg)  and Group 2(N=50) received programmed labor. The two groups were well matched in terms of age, weight, height, parity, baseline vitals and mean cervical dilatation at the time of administration of labor analgesia. Duration of analgesia, Visual analog scale score (VAS) and effect on ambulation (EOA) were recorded.

Result: All the parturients were assessed on the basis of VAS score on a scale of 0 to 10. One min after administration of labor analgesia, the mean VAS score in group 1(6.74±0.527) was significantly lower when compared with the mean VAS score in group2 (7.74±0.853) (p value = 0.000). The significant difference continued till 300 minutes. The mean duration of labor analgesia in group1 (238.96 ±21.888 min) was significantly more than the mean duration of analgesia in group 2 (98.4±23.505 min). In group 1 significantly more number of parturients had mild EOA till 25 min (P value 0.035). The mild EOA disappeared by 30 min and subsequently no EOA was observed in parturients receiving intrathecal analgesia.

Conclusion: Single shot intrathecal labor analgesia is a safe, effective, reliable, cheap and satisfactory method of pain relief during labor and delivery.

Keywords: Labor analgesia, Intrathecal labor analgesia, Visual analog scale (VAS) score, Effect on ambulation (EOA), Rescue analgesia, Maternal satisfaction.

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Corresponding Author

Dr Poonam

Address: H No. 687, Green field Avenue, Majitha road, Amritsar, Punajab, India