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Category: Volume 07 Issue 07 July 2019
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Title: Prevalence of Transfusion Transmissible Infections among Blood Donors at a Tertiary Care Hospital at Dhaka, Bangladesh

Authors: Dr Daanish Arefin Biswas, Dr Farida Parvin, Dr Bepasha Naznin, Dr Ferdous Ara, Dr Md. Ashraful Hoque, Dr Irani Begum, Dr Kamrul Islam Khan Emon

 DOI: https://dx.doi.org/10.18535/jmscr/v7i7.60

Abstract

Background: Disease transmission can occurs easily by transfusion of blood and components therapy. So screening is mandatory for all donated blood units for five transfusion transmitted diseases. It is necessary to know the current trends in results of screening for TTI in Bangladesh.

Objective: The present study was executed to assess the prevalence of infectious disease markers among donors at the blood bank of a tertiary care center, Sir Salimullah Medical College & Mitford Hospital at Dhaka.

Materials and Methods: The study was a three year (2016-2018) retrospective study. A total of 35,831 donors comprising of 32606(91%) males and 3225(9%) females were screened over 3 years. There are no paid donors, all are either voluntary or replacement donors. Data was accumulated and analyzed from blood bank records for all donors who were screened for various TTIs using respective immunological methods.

Results: Mean percentage of these infections per year was found to be Hepatitis B surface antigen (HBsAg) was 1.27%, Hepatitis C virus (HCV) was 0.013%,HIV was 0.0028%, syphilis was 0.078% andmalarial parasite (MP) was 0.0028%.The overall seroreactivity in present study significantly diminished through successive years.

Conclusions: The risk of transfusion transmissible infection (TTI) today is low but attention should be paid onmethods to ensure a safety blood supply. For that screening with a better selection of donors and use of sensitive screening tests including nucleic acid testing technology should be implemented.

Keywords: Transfusion transmitted infections, Blood Donors, Prevalence, HBV, HCV.

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Corresponding Author

Dr Md. Ashraful Hoque

CMBT, MIS, DGHS, Bangladesh