Title: Histopathological Spectrum of Posterior Cranial Fossa Lesion: At Tertiary Care Center
Authors: Saini Sunita, Mathur Kusum, Saini Vikas
DOI: https://dx.doi.org/10.18535/jmscr/v7i7.51
Abstract
Background: Posterior cranial fossa is a space located between the Foramen Magnum and Tentorium Cerebelli. It includes cerebellum, pons and medulla oblongata. Tumor of posterior cranial fossa can involve any of the above structures and can produce pressure symptoms, neurological deficits or sometimes even death. This study has been conducted at S.M.S. medical collage Jaipur from January 2017 to May 2019.
Aims and Objectives: To find incidence and histomorphological pattern of posterior cranial fossa lesion; at our tertiary care center.
Material and Methods: It was a retrospective study in which 280 consecutive cases of posterior cranial fossa tumors in children and adults are studies from January 2017 to May 2019.
Results: Among 280 cases, 155 were male and 125 were female patient. The morphological distribution of posterior cranial fossa lesion was as follows:- 102 cases Schwannoma, 38 cases Medulloblastoma, 31 Pilocytic astrocytoma, 25 cases Epidermoid cyst, 23 cases Meningioma, 14 cases Hemangioblastoma, 11 cases metastatic carcinoma, 7 cases Glioblastoma WHO grade 4, 5 cases ependymomas, 4 cases A-V malformation and abscess, 3 cases of low grade astrocytoma and arachnoid cyst each, 2 cases choroid plexus papilloma and 1 case of each paraganglioma, TB, hemangiopericytoma WHO grade 2, ependymal cyst, AT/RT, colloid cyst, oligodendroglioma.
Conclusions: Posterior cranial fossa involve cerebellum, pons and medulla oblongata.These organ are vital organ so involvement of posterior fossa is very dangerous may lead to death. Most common benign tumor was Schwannoma and most common malignant was Medulloblastoma.
Keyword: Posterior cranial fossa, medulloblastoma, pilocytic astrocytoma.
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