Title: Tuberculosis of the Breast- A Rare Entity

Authors: Mohit Rajpal, Amrita Kulhria, Amit Sammi

 DOI: https://dx.doi.org/10.18535/jmscr/v7i7.19

Abstract

Introduction: Tuberculosis of the breast is an uncommon disease accounting less than 0.1% of breast conditions in developed countries and 3–4% in regions, where the disease presents with high incidence (India, Africa). Misdiagnosis is common in biopsy and aspiration smears as it is usually paucibacillary. In most cases, cultures are also negative. It often mimics breast carcinoma and pyogenic breast abscess both clinically and radiologically.

Case Report: We report a case of mammary tuberculosis in a 25 year old lactating female, who presented in surgery OPD at Adesh Medical College and Hospital with painful lump in the left breast since one year.

Conclusion: Mammary tuberculosis is a rare disease. It can be deceptive to radiologist and surgeons as it can mimic carcinoma. Definitive diagnosis relies on demonstration of acid fast bacilli either on microscopy, culture or molecular studies such as polymerase chain reaction.  Polymerase chain reaction has good sensitivity for detection.

References

  1. Luh SP, Chang KJ, Cheng JH, Hsu JD, Huang CS. Surgical treatment for primary mammary tuberculosis – report of three octogenarian cases and review of literature. Breast Journal 2008; 14: 311–12.
  2. Maroulis I, Spyropoulos C, Zolota V, Tzorakoleftherakis E. Mammary tuberculosis mimicking breast cancer: a case report. Journal of Medicine Case Reports 2008; 2: 34.
  3. Cooper A. Illustrations of the diseases of the breast. London: Longman, Rees, Orme, Brown and Green; 1829.
  4. da Silva BB, Lopes-Costa PV, Pires CG, Pereira-Filho JD, dos Santos AR. Tuberculosis of the breast: analysis of 20 cases and a literature review. Transactions of the Royal Society of Tropical Medicine and Hygiene 2009; 103: 559–63.
  5. Madhusudhan KS, Gamanagatti S. Primary breast tuberculosis masquerading as carcinoma. Singapore Medical Journal 2008; 49:3–5.
  6. Mirsaeidi SM, Masjedi MR, Mansouri SD, Velayati AA. Tuberculosis of the breast: report of 4 clinical cases and literature review. East Mediterranean Health Journal 2007; 13: 670–76.
  7. Jah A, Mulla R, Lawrence FD, Pittam M, Ravichandran D. Tuberculosis of the breast: experience of a UK breast clinic serving an ethnically diverse population. Annals of the Royal College of Surgeons of England 2004; 86: 416–19.
  8. Teo TH, Ho GH, Chaturverdi A, Khoo BK. Tuberculosis of the chest wall: unusual presentation as a breast lump. Singapore Medical Journal 2009; 50: 97–99
  9. Fadaei-Araghi M, Geranpayeh L, Irani S, Matloob R, Kuraki S. Breast tuberculosis: report of eight cases. Archives of Iranian Medicine 2008; 11: 463–65.
  10. Kakkar S, Kapila K, Sing MK, Verma K. Tuberculosis of the breast. A cytomorphological study. Acta Cytol 2000; 44: 292-96.

Corresponding Author

Amrita Kulhria

Addresses: Department of Pathology, B.P.S. Government Medical College For Women, Khanpur Kalan, Sonipat Haryana. 131305, India