Title: NCCT Head findings in patients of chronic renal failure with altered sensorium presenting in a tertiary care centre

Authors: Dr Achint Singh, Dr Vinod Kumar, Dr Ritu Bhagat

 DOI: https://dx.doi.org/10.18535/jmscr/v7i4.59

Abstract

Introduction: Central nervous system (SNS) is commonly affected in uremics and also has been investigated variably in these patients. Various hypothesis have been postulated from time to time regarding etiology of the central nervous system tract lesions in chronic renal failure. Urea has been implicated in most of the studies.

Aim: The objective is to study the NCCT Head findings in patients of chronic renal failure.

Materials and Methods: This is a prospective study for a period of one year from nov. 2016 to oct. 2017 conducted at GMC, Jammu which is a tertiary care centre. In our study 64 patients were enrolled, 36 (56.25%) were males and 28 (43.75) were females. Age of patients ranged from 18 to 60 years.

Results: out of 64 patients undertaken in our study, 8 patients (12.5%) had ischaemic stroke, 6 patients (9.37%) had haemorrhagic stroke while 2 patients (3.12%) had both the lesions.

Conclusion: Neurological manifestations have been frequently reported in patients of chronic renal failure. Patients of CKD have moderate to severe chronic cognitive impairment, yet it is largely undiagnosed.

Keywords: central nervous system, chronic renal failure, glomerular filtration rate.

References

  1. Murray AM et al. Congnitive impairment in the Aging Dialysis and Chronic Kidney Disease populations: an occult burden. Adv Chronic Kidney Dis 2008 Apr: 15(2); 123-32.
  2. Cusmano F, Savazzi GM. Cerebral computer tomography in uremic and hemodialysis patients. J Comput Assist Tomogr 1986 July-Aug; 10(4): 567-70.
  3. Savazzi GM, Cusmano F et al. Cerebral Imaging Changes in patients with Chronic Renal Failure Treated Conservatively or in Hemodialysis. Nephron 2001; 89: 31-36.
  4. Rama Krishna, G.S.R. Krishna et al. Stroke in Chronic Kidney Disease. Indian J Nephrol 2009 Jan; 19(1): 5-7.
  5. Naresh, A.Y. Lakshmi et al. Stroke in Chronic Kidney Disease. Indian J Nephrol 2009 Jan; 19(1): 5-7.
  6. Eun Ja Lee, Jong HO Park et al. Acute bilateral basal ganglia lesions in diabetic uremia: diffusion weighted MRI. Neuroimaging 2007; 49: 1009.
  7. Wang HC, Cheng SJ. The syndrome of acute bilateral basal ganglia lesions in diabetic uremic patients. J. Neurol 2003 Aug; 250(8): 948-55.
  8. Nadia kousar et al. A Review of Risk Factors for Stroke in patients with Chronic Kidney Disease. J Vasc Interv Neurol 2009 Jan; 2(1): 126-31.

Corresponding Author

Dr Vinod Kumar 

R/O lane no 4 house no 2 Bandhu Rakh Kunjwani-Jammu (J&k) Pin 180010, India

Email: This email address is being protected from spambots. You need JavaScript enabled to view it., Mobile: 919419965435