Title: Rare Case of Primary Hemophagocytic Lymphohistiocytosis: A Case Report
Authors: Dr Anurita Saigal, Dr Anchana Gulati, Dr Sudarshan Kumar Sharma, Dr Rajni Kaushik
Hemophagocytic lymphohistiocytosis (HLH) is a fatal disease in which uncontrolled activation of immune system occurs. It is characterized by fever, pancytopenia, splenomegaly and hemophagocytosis in bone marrow, liver or lymph nodes. It has been associated with viral, bacterial, fungal and parasitic infection. An early diagnosis and treatment is the key to decrease the mortality .We report a case of hemophagocytic lymphohistiocytosis in a 39 year old male patient presenting with prolonged fever, pancytopenia, hepatosplenomegaly.
Keywords: Hemophagocytic lymphohistiocytosis; Macrophage, immune activation.