Title: Lipid profile in Chronic Kidney Disease before and after hemodialysis
Authors: Dr Rupam Kumari, Dr Chakradhar Majhi, Dr L.K. Dash
Introduction: cardiovascular complications were the major cause of mortality morbidity and mortality in hemodialysis patients.
Objective: To know the effect of hemodialysis on lipid profile in CKD patients.
Study Design: Hospital based observational study.
Study Setting: This study was done in department of general medicine VIMSAR,Burla, Odisha.
Study Duration: Nov 2016 to Oct 2018(24 Months).
Subjects and Methods: 100 patients of CKD on maintenance Hemodialysis were selected as study population diabetic Mellitus, liver disease and other causes of Dyslipidemia and metabolic were kept as exclusion criteria. Serum lipid profile was measured at the start of hemodialysis and subsequently after 6 months and 12 months of maintenance hemodialysis and those values were tabulated for comparison.
Results: In our study, serum triglyceride value after 6 months and 1 year after maintenance hemodialysis, was significantly elevated and serum HDL was significantly decreased as compared to those predialysis values.
Conclusion: Dyslipidemia is common in CKD Patients, Maintenance hemodialysis further deteriorates dyslipidemia in the form of further increase in serum triglyceride and decrease in HDL .This increase in risk of cardiovascular disease and further progression of CKD.
Keywords: Chronic kidney disease, dyslipidemia, lipid profile , HDL,hemodialysis.