Title: Histopathological study of endometrial biopsies in women presenting with abnormal uterine bleeding
Authors: Dr Moizah Najam, Dr Bharathi M
Abnormal uterine bleeding (AUB) is the most common presenting complaint in women attending the gynaecological outpatient department. Endometrial sampling could be used as the first diagnostic step in the evaluation of AUB. This study is done to evaluate histopathology of endometrium for identifying the various endometrial causes of AUB. Patients who presented with AUB and had undergone endometrial sampling are studied. A total of 180 cases are included in this study. Out of 180, 35 cases were excluded due to inadequate sampling. The age groups are categorised into reproductive (21-40years), perimenopausal (41-50 years), postmenopausal (>50years). The most common age group presenting with AUB in our study is perimenopausal group (44.13%). The most common pattern in this age is proliferative endometrium (32.81%). The most common cause in reproductive age group is also proliferative endometrium (48.33%), whereas that in the post-menopausal age group is Hyperplasia without atypia(33.33%).The other causes identified in various age groups are endometrial polyp (2.7%), retained products of conception (1.37%), hyperplasia without atypia (17.93%), hyperplasia with atypia(2.06%) and endometrial carcinoma(6.89%).A thorough histological study of endometrial biopsies can be used as first diagnostic step in evaluating the cause of AUB especially in postmenopausal women who are at increased risk for developing carcinoma.
Keywords: Abnormal uterine bleeding (AUB), proliferative endometrium, hyperplasia without atypia.