Title: Association of Vitamin D deficiency and Hypothyroidism in a tertiary teaching hospital in Kerala

Authors: Suma Samuel, Jacob K Jacob, Jilse George, Manjula V.D.

 DOI: https://dx.doi.org/10.18535/jmscr/v7i4.01

Abstract

Background: Vitamin D deficiency is a global health issue and is associated with myriad health disorders.

Objective:  To study the association of Vitamin D levels in hypothyroid patients to find out if low levels of Vitamin D is contributing to hypothyroid states.

Materials and Methods: A cross sectional case control observational study in a single center. The study was conducted in Government Medical College, Ernakulam in the medical department. Vitamin D levels in 60 hypothyroid patients which formed the case group and 60 matched control group was estimated using the Chemiluminescent immune assay during June2016 to December 2018, after obtaining approval of the Institutional Ethics Committee.

Results and Conclusions: This study has revealed that there was a significant number of patients with Vitamin D insufficiency in both groups with a statistically significant difference in females outnumbering males in vitamin D deficiency. However it was found that Vitamin D insufficiency was not present among hypothyroid patients significantly compared to euthyroid patients in the given study population.

Recommendations: The significant prevalence of low vitamin D levels in our population should be highlighted much more and should be a matter to bring in to more public awareness.

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Corresponding Author

Jacob K Jacob

Professor of Medicine, Government Medical College, Ernakulam, Kerala, India