Title: The correlation of peripheral neuropathy in children suffering from Type 1 diabetes Mellitus (IDDM) with duration of disease and degree of metabolic control by means of electrophysiological methods
Authors: Dr Sahila Muhammed Kunju, Dr S Abdul Gafoor
Patients with type 1 diabetes develop various complications (micro vascular and macro vascular) that can lead to cardiovascular disease, retinopathy, nephropathy, neuropathy, peripheral vascular disease, and other forms of end-organ damage. Duration and magnitude of hyperglycemia are both strongly correlated with the extent and rate of progression of diabetic micro vascular disease.
Objectives: To determine the correlation of peripheral neuropathy in children suffering from Type 1 diabetes Mellitus (IDDM) with duration of disease and degree of metabolic control by means of electrophysiological methods.
Materials and Method: Type 1 diabetic patients attending the Endocrinology outpatient clinic of the SAT Hospital, Thiruvananthapuram were taken as cases. Their detailed history and neurological evaluation are done. All patients undergo electrophysiological evaluation. The results are analysed.
Results: The degree of nerve abnormality showed correlation with duration of illness and degree of diabetic control. The number of nerves affected by diabetic neuropathy also increased with increasing duration of disease.
Conclusion: This study emphasizes the need for stricter diabetic control in children with type 1 DM.
Keywords: Type1 Diabetes Mellitus, Electrophysiological studies, Hyperglycemia.