Title: Histopathological Evaluation of Collagen Profiles in Spongiotic Dermatitis
Authors: Anjali Patankar, Ramya Gandhi*, Erli Amel Ivan
Context: Spongiotic Dermatitis is a common clinical condition also known as eczema, characterized by rashes and itching further may progress to scarring. The terms eczema and dermatitis are often used interchangeably to denote a polymorphic inflammatory reaction pattern involving the epidermis and dermis. Spongiosis refers to intraepidermal edema.
Aim: To assess the orientation of collagen in eczematous spongiotic dermatitis.
Material and Methods: The present study was done in the Department of Pathology, Sri Manakula Vinayagar Medical College, Pondicherry. Sixty diagnosed cases of spongiotic dermatitis diagnosed over a period of five years were taken in the study. Orientation of collagen was evaluated using Masson’s trichrome stain.
Results: Spongiotic dermatitis occurred in all age groups but commonly seen in middle age to elderly. Male to female ratio was 1:1.2 The most common symptom was itching (85%) followed by scaling(63.3%). Most common site was upper extremities (80%). subacute cases were predominantly seen (38.3%) followed by chronic cases (33.3%). The most common orientation of collagen seen was vertical (38.3%) which was seen in (50%) of chronic cases.
Conclusion: The study emphasizes the need of using masson trichrome on skin biopsy showing spongiotic dermatitis to assess the collagen orientation and to know its chronicity.
Keywords: Spongiotic dermatitis, collagen, masson’s trichrome.