Title: Prevalence of methicillin resistant of Staphylococcus aureus (MRSA) its antibiotic susceptibility pattern from various clinical specimens in a tertiary care hospital
Authors: Dr S. Senthamarai, Dr S. Sivasankari, Dr C. Anitha, Dr V.M. Somasunder, Dr K. Akila, Dr V.J. Shuba, S. Siji Mol, Dr K.Muthulakshmi
Background: MRSA causes significant therapeutic threat associated with increased morbidity and mortality.
Aim: This study was aimed to isolate the Staphylococcus aureus from various clinical specimens, evaluate its antibiotic susceptibility pattern and to study the prevalence of methicillin resistance among Staphylococcus aureus.
Materials and Method: This study was conducted at microbiology department, Meenakshi Medical College & Research Institute. Study period was from October 2017 to July 2018. All the clinical samples were collected with aseptic precautions &processed as per standard protocol. All the Staphylococcus aureus isolates were subjected for antibiotic susceptibility testing as per CLSI guidelines. Screening of MRSA was done using cefoxitin disc (30µg) as per CLSI recommended disc diffusion method.
Results: In our study 128 isolates isolated from various clinical samples were included. Majority (64.8%) of the isolates were from pus sample, followed by sputum. The prevalence of MRSA in our study is 21.87%. All the isolates were sensitive to Vancomycin and Linezolid which can be used as a drug of choice for MRSA strains.
Conclusion: This study insist the need of continuous monitoring the prevalence of MRSA in a given population and to frame the antibiotic policy because it can vary from region to region.
Keywords: MRSA, staphylococcus aureus, resistance.