Title: Quality of Life and Functional Disability in Patients with Obsessive Compulsive Disorder

Authors: Niska Sinha, Satish Kumar Sinha

 DOI: https://dx.doi.org/10.18535/jmscr/v7i2.21

Abstract

Background: Obsessive compulsive disorder (OCD) is an anxiety disorder which is chronic and incapacitating illness that causes profound impairment in psychosocial functioning and quality of life.

Materials and Methods: The present study was conducted with an aim to study the quality of life and disability between obsessive compulsive disorder and control group. A cross-sectional study was conducted with a sample size comprising of 40 patients of OCD and matched healthy controls after obtaining Ethical Committee approval. Patients were assessed using a semi-structured Socio-demographic proforma, Yale-Brown Obsessive-Compulsive Scale (Y-BOCS), Sheehan Disability Scale (SDS), WHO Quality of life-BREF (WHO-QOL-BREF). Data was evaluated using the Statistical Package for the Social Sciences (SPSS Inc. version 17.0).

Results: Poor quality of life in physical, psychological, social and environment domains as well as overall quality of life was found in OCD patient group as compared to control group. The OCD patient group was significantly more disabled compared to control group in work, social, environment domains as well as overall disability. Severity of OCD correlated positively with disability whereas it correlated negatively with quality of life.

Keywords: Quality of life, functional disability, obsessive compulsive disorder

References

  1. American Psychiatric Association. Diagnostic and statistical manual of mental disorders (Fifth ed.). Washington DC: American Psychiatric Association; 2013.
  2. Regier DA, Farmer ME, Rae DS, Myers JK, Kramer M, Robins LN. One-month prevalence of mental disorders in the United States and sociodemographic characteristics: The Epidemiologic Catchment Area study. Acta Psychiatrica Scandinavica 1993; 88:35–47.
  3. World Health Organization. The ‘newly defined’ burden of mental problems. Fact Sheet, No.217. Geneva, Switzerland: World Health Organization; 1999.
  4. Rapaport MH, Clary C, Fayyad R, Endicott J. Quality of life impairment in depressive and anxiety disorders. American Journal of Psychiatry 2005; 162:1171−78.
  5. Eisen JL, Mancebo MA, Pinto A, Coles ME, Pagano ME, Stout R. Impact of obsessive–compulsive disorder on quality of life. Comprehensive Psychiatry 2006; 47(4):270-5.
  6. Reddy YC, Srinath S, Prakash HM, Girimaji SC, Sheshadri SP, Khanna S. An overview of Indian research in Obsessive compulsive disorder. Indian Journal of Psychiatry 2010; 52:200-9.
  7. Storch EA, Abramowitz JS, Keeley M. Correlates and mediators of functional disability in obsessive–compulsive disorder. Depression and Anxiety 2009; 26(9):806-13.
  8. Bobes J, González MP, Bascarán MT, Arango C, Sáiz PA, Bousoño M. Quality of life and disability in patients with obsessive-compulsive disorder. Eur Psychiatry. 2001;16:239–45.
  9. World Health Organization. The Tenth Revision of the International Statistical Classification of Diseases and Related Health Problems (ICD-10): Diagnostic Criteria for Research. Geneva: World Health Organization; 1993.
  10. Goodman WK, Price LH, Rasmussen SA. The Yale-Brown Obsessive Compulsive Scale: Development, use, and reliability. Archives of General Psychiatry 1989; 46:1006-11.
  11. Sheehan DV, Harnett S, Raj BA. The measurement of disability. International Clinical Psychopharmacology 1996; 11(3):89-95.
  12. Yao G, Chang CW, Yu FC, Wang JD. Development and verification of validity and reliability of the WHOQOL-BREF. Journal of Formosan Medical Association 2002; 101:342-51.
  13. Khanna S, Reddy YJ. Obsessive Compulsive Disorder - an Indian perspective. Mumbai: Abbott India Lenbrook Division Publishing; 2004.
  14. Huppert JD, Simpson HB, Nissenson KJ, Liebowitz MR, Foa EB. Quality of life and functional impairment in obsessive–compulsive disorder: a comparison of patients with and without comorbidity, patients in remission, and healthy controls. Depression and Anxiety 2009; 26(1):39-45.
  15. Lopez AD, Murray CC. The global burden of disease:1990-2020. Nature Medicine 1998;4(11):1241-43.

Corresponding Author

Satish Kumar Sinha

Department of Psychiatry, Anugrah Narayan Medical College and Hospital, Gaya, Bihar, India

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