Title: Clinicopathological Spectrum of Uterine Sarcoma
Authors: Anila Tresa Alukal, Swathi B Shankar
Uterine sarcomas constitute about 1% of female genital tract malignancies. And 3% to 7% of Uterine cancer. Uterine sarcomas have an aggressive behaviour. Rarity of the tumour and histopathological diversity has contributed to the lack of consensus on risk factors. The aim of the study was to assess the epidemiological aspects, clinical features and histopathological features of uterine sarcomas.
Materials and Methods: A retrospective record based study of 32 diagnosed cases of uterine sarcoma over a period of 5 years (Jan 2010- Dec 2015) who had attended Dept. of Obstetrics and Gynaecology, Govt. Medical College Thrissur.Data was collected from the hospital records of 5 years. Variables studied include histology, age, parity, menopausal status, presenting symptoms, clinical features, co-morbidities, ultrasound findings, preoperative diagnosis, and stage of the disease.
Results: The most common histologic variety is Mixed malignant mullerian tumor (44%) followed by Leiomyosarcoma. (22%) MMMT is commonly seen in postmenopausal age group (79%) Leiomyosarcoma and Endometrial stromal sarcoma is mostly seen in the perimenopausal age group (45% & 57% respectively).
Keywords: uterine sarcoma; clinical features; pathological spectrum