Title: Comparative study of Endometrial Thickness with Histopathological pattern of Endmetrium in Postmenopausal Bleeding

Authors: Dr Shailesh Kumar Pankaj, Dr (Prof.) Lata Shukla Dwivedy, Dr Om Prakash Dwivedy

 DOI: https://dx.doi.org/10.18535/jmscr/v7i2.13

Abstract

Aims & Objective: The aim of the present study was to study endometrial thickness by transvaginal-sonography and correlate it with the Histopathological pattern in case of Post menopausal bleeding.   

Material & Methods: The present prospective cohort study was conduct in the Dept of Obst & Gynae& Pathology of Nalanda Medical College & Hospital, Patna from July 2015 to June 2017.   

Results: Out of 120 patients, majority 46 (38.33) had atrophic endometrium, endometrial hyperplasia in 28 (23.66%) out of which 22 had simple hyperplasia and 6 had atypical hyperplasia, endometrial polyp in 4 (3.33%) and two cases was confirmed as endometrial carcinoma on Histopathological examination. Majority of patients (40%) had ET <4mm. and 12 patient had ET >10mm.

In Patient with normal and atrophic histopathology, majority had ET <4 mm and those with hyperplasia had ET>4 and with polyp ET>6mm. No case of polyp and endometrial cancer was diagnosed at ET <6mm.    

Conclusion: Role of endometrial thickness cannot be ignored for detecting patients at high risk especially with co-morbid conditions. Histopathological evaluation is mandatory for ruling out malignancy is selected cases of post menopausal bleeding (PMB).      

Keywords:  Postmenopausal bleeding (PMB), TVS (Transvaginalsonography), ET (Endometrial thickness), Histopathological pattern of endometrium.

References

  1. Evaluation and management of postmenopausal bleeding. Indian Menopause Society. Guideline Number 4: August 2010.
  2. Karlsson B, Granberg S, Wikland M, et al. Transvaginalultrasonography of endometrium in women with postmenopausal bleeding –a Nordic multicenter study. Am J Obstet Gynecol. 1995; 172 (1488-149):4.
  3. Kaur M, Singh R, Sharma M. Endovaginalsonographic evaluation of postmenopausal uterine bleeding. J ClinDiagn Res. 2010, 4(2): 2175-82.
  4. Gerber B, Krause A, Kuelz T, et al. Rating of transvaginalsonography in the evaluation of postmenopausal bleeding ZentralblGynakol. 1999;121(3):143-8.

Corresponding Author

Dr (Prof.) Lata Shukla Dwivedy