Title: Study of Vitamin D3 Profile in Essential Hypertension
Authors: Shivani Bansal, Virendra Verma
Hypertension is the most common of the cardiovascular diseases, which is theleading cause of morbidity and mortality in the industrial world as well as becoming an increasing common disease in the developing countries. Hypertension is a major risk factor for renal, cerebrovascular and cardiovascular diseases. Therefore it is the most pressing health problems in the world. Hypertension is called the “silent killer” because it often has no warning signs or symptoms1. HTN is the most prevalent primary diagnosis reported in ambulatory care visits and its management accounts for 30% of office visits for individuals aged 45 to 65 years and more than 40% among those aged 64 and older2. In contrast, controlled blood pressure levels are associated with higher probability of survival rate until age 85 years and also increased longevity without co-morbidities1. However, despite advances in medical treatment and public campaigns to reduce the prevalence of hypertension, the disease remains a significant cause of health problems with huge health impacts mainly due to limited knowledge of risk factors related to the condition.
Another pandemic is Vitamin D insufficiency. Almost 50% of the world population is affected by Vitamin D insufficiency3. Vit D has known role in maintaining an adequate level of serum calcium, phosphorus, parathyroid hormone and normal bone metabolism alongwith there is evidence that Vit D has a biological effect more than mineral metabolism4. The majority of epidemiological studies have shown that Vit D deficiency is a major risk factor for arterial hypertension and cerebrovascular disease3.