Title: Adult Onset Still’s Disease as Differential Diagnosis of PUO: A Case Report
Authors: Manju, Dhiraj, B.D. Dogra, Pankaj, Gopal Singh, Ankita
Adult onset Still’s disease AOSD) is chronic multi-system inflammatory disorder of unknown etiology. It is characterized by high spiking fever, ployarthralgia and skin rash. Lymphadenopathy is another prominent feature of adult onset Still’s disease. The rarity of this diease has been associated with low index of suspicion3 among physicians and hence delayed diagnosis in patients suffering from it. We reported a 23 years old female presented with fever, myelgia, skin rashes and polyarthritis for 1.6 months, Examination revealed fever, typical skin rash, and polyarthritis for 1.6 months Examination revealed fever, typical skin rash and polyarthritis. On investigation there were neutrophilic leukocytosis, high ESR, high ferritin level, but RA test and ANA test, CPK and Jo-1 were negative. All of her history, clinical examinations and laboratory findings fulfill the diagnostic Yamaguchi criteria for AOSD. With proper treatment, now she is completely symptoms free and leaving a healthy life.
Keyworks: Fever, skin rash, polyarthritis, Adult onset Still’s disease and CPK