Title: Role of Bovine Colostrum in Healing of Chronic Non-Healing Ulcers – A Clinical Study

Authors: Ashok Kumar Panigrahi, Manoj Kumar Sahoo, Sabita Mohapatra, Debananda Tudu, Tanmaya Padhi, Ankita Panigrahy

 DOI:  https://dx.doi.org/10.18535/jmscr/v6i11.37

Abstract

This study was conducted to compare the efficacy of colostrum powder as an add on dressing with that of conventional dressing in the healing of chronic non-healing ulcer. Sixty patients with non-healing ulcer were treated with conventional dressing (povidone iodine, hydrogen peroxide) (Group 1) and another 60 patients were treated with add-on Bovine Colostrum (Group 2) for a period of 3 weeks. The healing of ulcer in both groups was determined by using Resvech Ulcer Healing Score (which utilizes 9 ulcer parameters) at weekly intervals for 3 weeks. There was highly significant increase in wound healing in the Bovine Colostrum treated group in comparision to the conventionally treated group, starting from first week upto third week. Bovine colostrum has significant wound healing property.

Keywords: Resvech Score, Conventional dressing, Diabetic Ulcer.

References

  1. Järbrink K, Ni G, Sönnergren H, Schmidtchen A, Pang C, Bajpai R, et al. Prevalence and incidence of chronic wounds and related complications: a protocol for a systematic review. 2016; 5(1):152.
  2. Shukla V, Ansari M, Gupta S. Wound Healing Research: A Perspective From India. Int J Low Extrem Wounds 2005;4(1):7–8.
  3. Ashu Rastogi AB. Diabetic Foot Infection : An Indian Scenario. 2016; 3(December): 71–9.
  4. L. Steed, M. W. Webster, J. J. Ricotta et al. Clinical evaluation of recombinant human platelet-derived growth factor for the treatment of lower extremity diabetic ulcers. Journal of Vascular Surgery, vol. 21, no. 1, pp. 71–81 1995.
  5. Restrepo-Medrano JC, Soriano JV. Development of a wound healing index for chronic wounds. EWMA J. 2012;12 (2):39–46.
  6. Kshirsagar AY, Vekariya MA, Gupta V, Pednekar AS, Mahna A, Patankar R, et al. A comparative study of colostrum dressing versus conventional dressing in deep wounds. J Clin Diagnostic Res. 2015;9(4): PC01-PC04.
  7. Thapa BR. Therapeutic potentials of bovine colostrums. Indian J Pediatr. 2005; 72(10): 849–52.
  8. Chatterjee S. Deep Wounds : Colostrum Dressing Versus Conventional Dressing. 2015;2(8):24–8.

Corresponding Author

Dr Manoj Kumarsahoo

Dept of Pharmacology, VIMSAR, Burla, Odisha., Pin -768017, India

Email: This email address is being protected from spambots. You need JavaScript enabled to view it., Mob No. 8763147949