Title: Renal Malakoplakia- A Case Report

Authors: Dr M.M.Litake, Dr Ashutosh Kumar

 DOI:  https://dx.doi.org/10.18535/jmscr/v6i11.18

Abstract

Malakoplakia is a rare granulomatous disease of infectious etiology. The name is derived from the Greek malakos (soft) and plakos (plaque), describing its usual clinical presentation as friable yellow soft plaques.

It was first described by Von Hansemann in 1901 and in 1902 by Michaelis and Gutmann. Total number of patients with malakoplakia is fewer than 500. Most patients have genitourinary tract disease.

We report a case of renal malakoplakia with end stage renal disease in a 42 years old female who presented with pain in the right lower abdomen for about 1 month. Investigations revealed a right kidney in the pelvic region which was non functional on DTPA scan. Right sided open nephrectomy was done. Histopathology suggested malakoplakia with end stage renal disease.

This rare entity is associated with a non- specific clinical presentation. In the imaging studies the appearance of the affected kidneys ranges from a normal kidney to an enlarged, nonfunctioning kidney.

References

  1. Wielenberg AJ, Demos TC, Rangachari B, Turk T: Malakoplakia presenting as a solitary renal mass. Am J Roentgenol 2004, 183(6): 1703-1705.
  2. Abolhasani et al.: Renal malakoplakia presenting as a renal mass in a 55 year old man: a case report. Journal of Medical Case Reports 2012 6:379
  3. Saleem MA, Milford DV, Raafat F et al. Renal parenchymal malakoplakia- a case report and review of literature. Pediatr. Nephrol. 1993: 7: 256-8.
  4. Pusl T, Weiss M, Hartmann B et al. Malakoplakia in a renal transplant recipient. Eur. J. Intern .Med . 2006; 17: 133-5.

Corresponding Author

Dr Ashutosh Kumar